4n5b

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m (Protected "4n5b" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4n5b| PDB=4n5b | SCENE= }}
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===Crystal structure of the Nipah virus phosphoprotein tetramerization domain===
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{{ABSTRACT_PUBMED_24155387}}
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The entry 4n5b is ON HOLD
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==About this Structure==
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[[4n5b]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N5B OCA].
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Authors: Bruhn-Johannsen, J.F., Barnett, K., Bibby, J., Thomas, J., Keegan, R., Rigden, D., Bornholdt, Z.A., Saphire, E.O.
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==Reference==
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<ref group="xtra">PMID:024155387</ref><references group="xtra"/><references/>
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Description: Crystal structure of the Nipah virus phosphoprotein tetramerization domain
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[[Category: Barnett, K.]]
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[[Category: Bibby, J.]]
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[[Category: Bornholdt, Z A.]]
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[[Category: Bruhn, J F.]]
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[[Category: Keegan, R.]]
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[[Category: Rigden, D.]]
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[[Category: Saphire, E O.]]
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[[Category: Thomas, J.]]
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[[Category: Interferon inhibitor]]
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[[Category: Nucleoprotein chaperone]]
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[[Category: Viral polymerase co-factor]]
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[[Category: Viral protein]]

Revision as of 10:25, 27 November 2013

PDB ID 4n5b

Drag the structure with the mouse to rotate
4n5b, resolution 2.20Å ()
Ligands:
Gene: P/V/W/C (NIPAV)


Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml


Crystal structure of the Nipah virus phosphoprotein tetramerization domain

Publication Abstract from PubMed

The Nipah virus phosphoprotein, P, is multimeric and tethers the viral polymerase to the nucleocapsid. We present the crystal structure of the multimerization domain of Nipah P: a long, parallel, tetrameric, coiled coil with a small, alpha-helical cap structure. Across the paramyxoviruses, these domains share little sequence identity; yet retain similar length and structural organization, suggesting a common requirement for scaffolding or spatial organization of the functions of P in the virus life cycle.

Crystal structure of the Nipah virus phosphoprotein tetramerization domain., Bruhn-Johannsen JF, Barnett K, Bibby J, Thomas J, Keegan R, Rigden D, Bornholdt ZA, Saphire EO, J Virol. 2013 Oct 23. PMID:24155387

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

About this Structure

4n5b is a 8 chain structure. Full crystallographic information is available from OCA.

Reference

  • Bruhn-Johannsen JF, Barnett K, Bibby J, Thomas J, Keegan R, Rigden D, Bornholdt ZA, Saphire EO. Crystal structure of the Nipah virus phosphoprotein tetramerization domain. J Virol. 2013 Oct 23. PMID:24155387 doi:http://dx.doi.org/10.1128/JVI.02294-13

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