4hvq
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4hvq| PDB=4hvq | SCENE= }} | |
| + | ===X-ray crystal structure of FECU reconstituted 3-hydroxyanthranilate-3,4-dioxygenase from cupriavidus metallidurans=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/3HAO_RALME 3HAO_RALME]] Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.<ref>PMID:15909977</ref> | ||
| - | + | ==About this Structure== | |
| + | [[4hvq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HVQ OCA]. | ||
| - | + | ==Reference== | |
| + | <references group="xtra"/><references/> | ||
| + | [[Category: 3-hydroxyanthranilate 3,4-dioxygenase]] | ||
| + | [[Category: Chen, L.]] | ||
| + | [[Category: Liu, A.]] | ||
| + | [[Category: Liu, F.]] | ||
| + | [[Category: Bi-cupin iron-binding]] | ||
| + | [[Category: Dioxygenase]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 10:30, 27 November 2013
Contents |
X-ray crystal structure of FECU reconstituted 3-hydroxyanthranilate-3,4-dioxygenase from cupriavidus metallidurans
Function
[3HAO_RALME] Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.[1]
About this Structure
4hvq is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- ↑ Colabroy KL, Zhai H, Li T, Ge Y, Zhang Y, Liu A, Ealick SE, McLafferty FW, Begley TP. The mechanism of inactivation of 3-hydroxyanthranilate-3,4-dioxygenase by 4-chloro-3-hydroxyanthranilate. Biochemistry. 2005 May 31;44(21):7623-31. PMID:15909977 doi:http://dx.doi.org/10.1021/bi0473455
