4hvr

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'''Unreleased structure'''
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{{STRUCTURE_4hvr| PDB=4hvr | SCENE= }}
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===X-ray crystal structure of salicylic acid bound 3-hydroxyanthranilate-3,4-dioxygenase from cupriavidus metallidurans===
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The entry 4hvr is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/3HAO_RALME 3HAO_RALME]] Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.<ref>PMID:15909977</ref>
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Authors: Liu, F, Chen, L, Liu, A
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==About this Structure==
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[[4hvr]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HVR OCA].
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Description: X-ray crystal structure of salicylic acid bound 3-hydroxyanthranilate-3,4-dioxygenase from cupriavidus metallidurans
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==Reference==
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<references group="xtra"/><references/>
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[[Category: 3-hydroxyanthranilate 3,4-dioxygenase]]
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[[Category: Chen, L.]]
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[[Category: Liu, A.]]
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[[Category: Liu, F.]]
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[[Category: Bi-cupin iron-binding]]
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[[Category: Dioxygenase]]
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[[Category: Oxidoreductase]]

Revision as of 10:30, 27 November 2013

Template:STRUCTURE 4hvr

Contents

X-ray crystal structure of salicylic acid bound 3-hydroxyanthranilate-3,4-dioxygenase from cupriavidus metallidurans

Function

[3HAO_RALME] Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.[1]

About this Structure

4hvr is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Colabroy KL, Zhai H, Li T, Ge Y, Zhang Y, Liu A, Ealick SE, McLafferty FW, Begley TP. The mechanism of inactivation of 3-hydroxyanthranilate-3,4-dioxygenase by 4-chloro-3-hydroxyanthranilate. Biochemistry. 2005 May 31;44(21):7623-31. PMID:15909977 doi:http://dx.doi.org/10.1021/bi0473455

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