4lij

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'''Unreleased structure'''
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{{STRUCTURE_4lij| PDB=4lij | SCENE= }}
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===Crystal structure of a far upstream element (FUSE) binding protein 1 (FUBP1) from Homo sapiens at 1.95 A resolution===
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The entry 4lij is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/FUBP1_HUMAN FUBP1_HUMAN]] Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription.<ref>PMID:8125259</ref>
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Authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology, Partnership for T-Cell Biology (TCELL)
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==About this Structure==
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[[4lij]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LIJ OCA].
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Description: Crystal structure of a far upstream element (FUSE) binding protein 1 (FUBP1) from Homo sapiens at 1.95 A resolution
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Biology, Partnership for T-Cell.]]
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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[[Category: TCELL, Partnership for T-Cell Biology.]]
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[[Category: Jcsg]]
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[[Category: Joint center for structural genomic]]
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[[Category: Kh domain]]
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[[Category: Pf00013]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-biology]]
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[[Category: Rna-binding protein]]
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[[Category: Structural genomic]]

Revision as of 10:33, 27 November 2013

Template:STRUCTURE 4lij

Contents

Crystal structure of a far upstream element (FUSE) binding protein 1 (FUBP1) from Homo sapiens at 1.95 A resolution

Function

[FUBP1_HUMAN] Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription.[1]

About this Structure

4lij is a 3 chain structure. Full crystallographic information is available from OCA.

Reference

  1. Duncan R, Bazar L, Michelotti G, Tomonaga T, Krutzsch H, Avigan M, Levens D. A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif. Genes Dev. 1994 Feb 15;8(4):465-80. PMID:8125259

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