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4mqt

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_4mqt| PDB=4mqt | SCENE= }}
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===Structure of active human M2 muscarinic acetylcholine receptor bound to the agonist iperoxo and allosteric modulator LY2119620===
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The entry 4mqt is ON HOLD
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==Disease==
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[[http://www.uniprot.org/uniprot/ACM2_HUMAN ACM2_HUMAN]] Disease susceptibility is associated with variations affecting the gene represented in this entry.
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Authors: Kruse, A.C., Ring, A.M., Manglik, A., Hu, J., Hu, K., Eitel, K., Huebner, H., Pardon, E., Valant, C., Sexton, P.M., Christopoulos, A., Felder, C.C., Gmeiner, P., Steyaert, J., Weis, W.I., Garcia, K.C., Wess, J., Kobilka, B.K.
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==Function==
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[[http://www.uniprot.org/uniprot/ACM2_HUMAN ACM2_HUMAN]] The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition.
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Description: Structure of active human M2 muscarinic acetylcholine receptor bound to the agonist iperoxo and allosteric modulator LY2119620
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==About this Structure==
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[[4mqt]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MQT OCA].
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[[Category: Christopoulos, A.]]
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[[Category: Eitel, K.]]
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[[Category: Felder, C C.]]
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[[Category: Garcia, K C.]]
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[[Category: Gmeiner, P.]]
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[[Category: Hu, J.]]
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[[Category: Hu, K.]]
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[[Category: Huebner, H.]]
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[[Category: Kobilka, B K.]]
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[[Category: Kruse, A C.]]
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[[Category: Manglik, A.]]
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[[Category: Pardon, E.]]
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[[Category: Ring, A M.]]
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[[Category: Sexton, P M.]]
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[[Category: Steyaert, J.]]
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[[Category: Valant, C.]]
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[[Category: Weis, W I.]]
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[[Category: Wess, J.]]
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[[Category: Allosteric modulation]]
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[[Category: G protein-coupled receptor]]
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[[Category: Muscarinic acetylcholine receptor]]
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[[Category: Signaling protein]]

Revision as of 10:35, 27 November 2013

Template:STRUCTURE 4mqt

Contents

Structure of active human M2 muscarinic acetylcholine receptor bound to the agonist iperoxo and allosteric modulator LY2119620

Disease

[ACM2_HUMAN] Disease susceptibility is associated with variations affecting the gene represented in this entry.

Function

[ACM2_HUMAN] The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition.

About this Structure

4mqt is a 2 chain structure. Full crystallographic information is available from OCA.

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4mqt"
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