4lk1
From Proteopedia
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{{STRUCTURE_4lk1| PDB=4lk1 | SCENE= }} | {{STRUCTURE_4lk1| PDB=4lk1 | SCENE= }} | ||
===Crystal Structure Analysis of the E.coli holoenzyme=== | ===Crystal Structure Analysis of the E.coli holoenzyme=== | ||
| + | {{ABSTRACT_PUBMED_24218560}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
| - | [[4lk1]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LK1 OCA]. | + | [[4lk1]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobw Ecobw], [http://en.wikipedia.org/wiki/Ecod1 Ecod1] and [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LK1 OCA]. |
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:024218560</ref><references group="xtra"/><references/> | ||
[[Category: DNA-directed RNA polymerase]] | [[Category: DNA-directed RNA polymerase]] | ||
| + | [[Category: Ecobw]] | ||
| + | [[Category: Ecod1]] | ||
| + | [[Category: Ecoli]] | ||
[[Category: Bae, B.]] | [[Category: Bae, B.]] | ||
[[Category: Darst, S A.]] | [[Category: Darst, S A.]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 05:48, 4 December 2013
Contents |
Crystal Structure Analysis of the E.coli holoenzyme
Template:ABSTRACT PUBMED 24218560
Function
[C9QUL2_ECOD1] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).[HAMAP-Rule:MF_00366][SAAS:SAAS012293_004_017283] [C9QXI7_ECOD1] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).[HAMAP-Rule:MF_00059] [C5A0S8_ECOBW] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).[SAAS:SAAS012754_004_011999] [C9QV90_ECOD1] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).[HAMAP-Rule:MF_01321][RuleBase:RU000432] [RPOD_ECOLI] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium.
About this Structure
4lk1 is a 12 chain structure with sequence from Ecobw, Ecod1 and Ecoli. Full crystallographic information is available from OCA.
Reference
- Bae B, Davis E, Brown D, Campbell EA, Wigneshweraraj S, Darst SA. Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma70 domain 1.1. Proc Natl Acad Sci U S A. 2013 Nov 11. PMID:24218560 doi:http://dx.doi.org/10.1073/pnas.1314576110
