This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4cb9

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_4cb9| PDB=4cb9 | SCENE= }}
 +
===Structure of full-length CTNNBL1 in P43212 space group===
 +
{{ABSTRACT_PUBMED_24269683}}
-
The entry 4cb9 is ON HOLD
+
==Function==
 +
[[http://www.uniprot.org/uniprot/CTBL1_HUMAN CTBL1_HUMAN]] Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.<ref>PMID:12659813</ref> <ref>PMID:18722174</ref>
-
Authors: Ganesh, K., vanMaldegem, F., Telerman, S.B., Simpson, P., Johnson, C.M., Williams, R.L., Neuberger, M.S., Rada, C.
+
==About this Structure==
 +
[[4cb9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CB9 OCA].
-
Description: Structure of full-length CTNNBL1 in P43212 space group
+
==Reference==
 +
<ref group="xtra">PMID:024269683</ref><references group="xtra"/><references/>
 +
[[Category: Ganesh, K.]]
 +
[[Category: Johnson, C M.]]
 +
[[Category: Neuberger, M S.]]
 +
[[Category: Rada, C.]]
 +
[[Category: Simpson, P.]]
 +
[[Category: Telerman, S B.]]
 +
[[Category: Williams, R L.]]
 +
[[Category: VanMaldegem, F.]]
 +
[[Category: Aid]]
 +
[[Category: Apoptosis]]
 +
[[Category: Deaminase]]
 +
[[Category: Import]]

Revision as of 07:18, 4 December 2013

Template:STRUCTURE 4cb9

Contents

Structure of full-length CTNNBL1 in P43212 space group

Template:ABSTRACT PUBMED 24269683

Function

[CTBL1_HUMAN] Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.[1] [2]

About this Structure

4cb9 is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Ganesh K, van Maldegem F, Telerman SB, Simpson P, Johnson CM, Williams RL, Neuberger MS, Rada C. Structural and mutational analysis reveals that CTNNBL1 binds NLSs in a manner distinct from that of its closest armadillo-relative, karyopherin alpha FEBS Lett. 2013 Nov 20. pii: S0014-5793(13)00847-8. doi:, 10.1016/j.febslet.2013.11.013. PMID:24269683 doi:http://dx.doi.org/10.1016/j.febslet.2013.11.013
  1. ↑ Jabbour L, Welter JF, Kollar J, Hering TM. Sequence, gene structure, and expression pattern of CTNNBL1, a minor-class intron-containing gene--evidence for a role in apoptosis. Genomics. 2003 Mar;81(3):292-303. PMID:12659813
  2. ↑ Conticello SG, Ganesh K, Xue K, Lu M, Rada C, Neuberger MS. Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1. Mol Cell. 2008 Aug 22;31(4):474-84. doi: 10.1016/j.molcel.2008.07.009. PMID:18722174 doi:10.1016/j.molcel.2008.07.009

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4cb9"
Personal tools