4m17

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'''Unreleased structure'''
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{{STRUCTURE_4m17| PDB=4m17 | SCENE= }}
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===Crystal Structure of Surfactant Protein-D D325A/R343V mutant===
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{{ABSTRACT_PUBMED_24224757}}
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The entry 4m17 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/SFTPD_HUMAN SFTPD_HUMAN]] Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
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Authors: Goh, B.C., Rynkiewicz, M.J., Cafarella, T.R., White, M.R., Hartshorn, K.L., Allen, K., Crouch, E.C., Calin, O., Seeberger, P.H., Schulten, K., Seaton, B.A.
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==About this Structure==
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[[4m17]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M17 OCA].
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Description: Crystal Structure of Surfactant Protein-D D325A/R343V mutant
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==Reference==
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<ref group="xtra">PMID:024224757</ref><references group="xtra"/><references/>
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[[Category: Allen, K.]]
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[[Category: Cafarella, T R.]]
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[[Category: Calin, O.]]
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[[Category: Crouch, E C.]]
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[[Category: Goh, B C.]]
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[[Category: Hartshorn, K L.]]
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[[Category: Rynkiewicz, M J.]]
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[[Category: Schulten, K.]]
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[[Category: Seaton, B A.]]
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[[Category: Seeberger, P H.]]
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[[Category: White, M R.]]
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[[Category: Carbohydrate recognition domain]]
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[[Category: Lectin]]
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[[Category: Sugar binding protein]]
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[[Category: Surfactant protein]]

Revision as of 07:21, 4 December 2013

Template:STRUCTURE 4m17

Contents

Crystal Structure of Surfactant Protein-D D325A/R343V mutant

Template:ABSTRACT PUBMED 24224757

Function

[SFTPD_HUMAN] Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.

About this Structure

4m17 is a 12 chain structure. Full crystallographic information is available from OCA.

Reference

  • Goh BC, Rynkiewicz MJ, Cafarella TR, White MR, Hartshorn KL, Allen K, Crouch EC, Calin O, Seeberger PH, Schulten K, Seaton BA. Molecular mechanisms of inhibition of influenza by surfactant protein d revealed by large-scale molecular dynamics simulation. Biochemistry. 2013 Nov 26;52(47):8527-38. doi: 10.1021/bi4010683. Epub 2013 Nov, 13. PMID:24224757 doi:http://dx.doi.org/10.1021/bi4010683

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