4m17
From Proteopedia
(Difference between revisions)
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- | + | {{STRUCTURE_4m17| PDB=4m17 | SCENE= }} | |
+ | ===Crystal Structure of Surfactant Protein-D D325A/R343V mutant=== | ||
+ | {{ABSTRACT_PUBMED_24224757}} | ||
- | + | ==Function== | |
+ | [[http://www.uniprot.org/uniprot/SFTPD_HUMAN SFTPD_HUMAN]] Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. | ||
- | + | ==About this Structure== | |
+ | [[4m17]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M17 OCA]. | ||
- | + | ==Reference== | |
+ | <ref group="xtra">PMID:024224757</ref><references group="xtra"/><references/> | ||
+ | [[Category: Allen, K.]] | ||
+ | [[Category: Cafarella, T R.]] | ||
+ | [[Category: Calin, O.]] | ||
+ | [[Category: Crouch, E C.]] | ||
+ | [[Category: Goh, B C.]] | ||
+ | [[Category: Hartshorn, K L.]] | ||
+ | [[Category: Rynkiewicz, M J.]] | ||
+ | [[Category: Schulten, K.]] | ||
+ | [[Category: Seaton, B A.]] | ||
+ | [[Category: Seeberger, P H.]] | ||
+ | [[Category: White, M R.]] | ||
+ | [[Category: Carbohydrate recognition domain]] | ||
+ | [[Category: Lectin]] | ||
+ | [[Category: Sugar binding protein]] | ||
+ | [[Category: Surfactant protein]] |
Revision as of 07:21, 4 December 2013
Contents |
Crystal Structure of Surfactant Protein-D D325A/R343V mutant
Template:ABSTRACT PUBMED 24224757
Function
[SFTPD_HUMAN] Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
About this Structure
4m17 is a 12 chain structure. Full crystallographic information is available from OCA.
Reference
- Goh BC, Rynkiewicz MJ, Cafarella TR, White MR, Hartshorn KL, Allen K, Crouch EC, Calin O, Seeberger PH, Schulten K, Seaton BA. Molecular mechanisms of inhibition of influenza by surfactant protein d revealed by large-scale molecular dynamics simulation. Biochemistry. 2013 Nov 26;52(47):8527-38. doi: 10.1021/bi4010683. Epub 2013 Nov, 13. PMID:24224757 doi:http://dx.doi.org/10.1021/bi4010683