4mz3

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'''Unreleased structure'''
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{{STRUCTURE_4mz3| PDB=4mz3 | SCENE= }}
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===Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain, C131W mutant===
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The entry 4mz3 is ON HOLD until Paper Publication
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==Disease==
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[[http://www.uniprot.org/uniprot/SCN4B_HUMAN SCN4B_HUMAN]] Romano-Ward syndrome. The disease is caused by mutations affecting the gene represented in this entry.
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Authors: Das, S., Van Petegem, F.
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==Function==
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[[http://www.uniprot.org/uniprot/SCN4B_HUMAN SCN4B_HUMAN]] Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation (By similarity).
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Description: Crystal Structure of a mutant Ion Channel Domain
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==About this Structure==
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[[4mz3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MZ3 OCA].
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[[Category: Das, S.]]
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[[Category: Petegem, F Van.]]
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[[Category: Extracellular]]
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[[Category: Ion conductance]]
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[[Category: Membrane protein]]

Revision as of 07:34, 4 December 2013

Template:STRUCTURE 4mz3

Contents

Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain, C131W mutant

Disease

[SCN4B_HUMAN] Romano-Ward syndrome. The disease is caused by mutations affecting the gene represented in this entry.

Function

[SCN4B_HUMAN] Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation (By similarity).

About this Structure

4mz3 is a 2 chain structure. Full crystallographic information is available from OCA.

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OCA

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