Huan He/Sandbox1
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== Interleukin-1 beta(IL-1β) == | == Interleukin-1 beta(IL-1β) == | ||
| - | IL-1β along with IL-1α is one of cytokines secreted from local inflammatory cells, are belong to IL-1 family. while the former is dominate and they have been distinguished by the cell with which they interact. IL-1β precursor need to be activated by protease (convertase or IL-1β converting enzyme) to form IL-1 active species. The active mature IL-1 mediates several components of the acute phase reaction, including the febrile response, secretion of adrenocorticotropic hormone (ACIH), and the synthesis of | + | IL-1β along with IL-1α is one of cytokines secreted from local inflammatory cells, are belong to IL-1 family. while the former is dominate and they have been distinguished by the cell with which they interact. IL-1β precursor need to be activated by protease (convertase or IL-1β converting enzyme) to form IL-1 active species. The active mature IL-1 mediates several components of the acute phase reaction, including the febrile response, secretion of adrenocorticotropic hormone (ACIH), and the synthesis of [acute phase proteins][http://en.wikipedia.org/wiki/Acute-phase_protein]. |
interleukin 1(IL-1) cytokines could mediate innate and adaptive immunity[[1]]. | interleukin 1(IL-1) cytokines could mediate innate and adaptive immunity[[1]]. | ||
Revision as of 00:56, 6 December 2013
Contents |
Interleukin-1 beta(IL-1β)
IL-1β along with IL-1α is one of cytokines secreted from local inflammatory cells, are belong to IL-1 family. while the former is dominate and they have been distinguished by the cell with which they interact. IL-1β precursor need to be activated by protease (convertase or IL-1β converting enzyme) to form IL-1 active species. The active mature IL-1 mediates several components of the acute phase reaction, including the febrile response, secretion of adrenocorticotropic hormone (ACIH), and the synthesis of [acute phase proteins][1]. interleukin 1(IL-1) cytokines could mediate innate and adaptive immunity1.
HUMAN INTERLEUKIN-1 BETA
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TYPE-1 INTERLEUKIN-1 RECEPTOR COMPLEXED WITH INTERLEUKIN-1 BETA
STRUCTURE OF THE INTERLEUKIN-1BETA SIGNALING COMPLEX
