3ikf
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[3ikf]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3ikf]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pseudomallei"_whitmore_1913 "bacillus pseudomallei" whitmore 1913]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IKF OCA]. |
==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:021359640</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:021359640</ref><references group="xtra"/><references/> | ||
| + | [[Category: Bacillus pseudomallei whitmore 1913]] | ||
[[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]] | [[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]] | ||
| - | [[Category: Burkholderia pseudomallei]] | ||
[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]] | [[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]] | ||
[[Category: Fbdd]] | [[Category: Fbdd]] | ||
Revision as of 12:33, 11 December 2013
Contents |
Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with FOL fragment 717, imidazo[2,,1-b][1,3]thiazol-6-ylmethanol
Template:ABSTRACT PUBMED 21359640
Function
[ISPF_BURPS] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).[HAMAP-Rule:MF_00107]
About this Structure
3ikf is a 3 chain structure with sequence from "bacillus_pseudomallei"_whitmore_1913 "bacillus pseudomallei" whitmore 1913. Full crystallographic information is available from OCA.
See Also
Reference
- Begley DW, Hartley RC, Davies DR, Edwards TE, Leonard JT, Abendroth J, Burris CA, Bhandari J, Myler PJ, Staker BL, Stewart LJ. Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics. 2011 Jul;12(2):63-76. Epub 2011 Feb 26. PMID:21359640 doi:10.1007/s10969-011-9102-6
Categories: Bacillus pseudomallei whitmore 1913 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | SSGCID, Seattle Structural Genomics Center for Infectious Disease. | Fbdd | Fragment-based drug design | Isoprene biosynthesis | Lyase | Metal-binding | Niaid | Seattle structural genomics center for infectious disease | Ssgcid
