4m2z

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'''Unreleased structure'''
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{{STRUCTURE_4m2z| PDB=4m2z | SCENE= }}
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===Crystal structure of RNASE III complexed with double-stranded RNA and CMP (TYPE II CLEAVAGE)===
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{{ABSTRACT_PUBMED_24274754}}
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The entry 4m2z is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/RNC_AQUAE RNC_AQUAE]] Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.<ref>PMID:21138964</ref> <ref>PMID:16439209</ref>
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Authors: Gan, J., Liang, Y.-H., Shaw, G.X., Tropea, J.E., Waugh, D.S., Ji, X.
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==About this Structure==
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[[4m2z]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M2Z OCA].
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Description: Crystal structure of RNASE III complexed with double-stranded RNA and CMP (TYPE II CLEAVAGE)
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==Reference==
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<ref group="xtra">PMID:024274754</ref><references group="xtra"/><references/>
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[[Category: Ribonuclease III]]
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[[Category: Gan, J.]]
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[[Category: Ji, X.]]
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[[Category: Liang, Y H.]]
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[[Category: Shaw, G X.]]
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[[Category: Tropea, J E.]]
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[[Category: Waugh, D S.]]
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[[Category: Dsrna]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-rna complex]]
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[[Category: Rna binding]]
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[[Category: Rna processing]]
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[[Category: Rnase iii]]

Revision as of 13:32, 11 December 2013

Template:STRUCTURE 4m2z

Contents

Crystal structure of RNASE III complexed with double-stranded RNA and CMP (TYPE II CLEAVAGE)

Template:ABSTRACT PUBMED 24274754

Function

[RNC_AQUAE] Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.[1] [2]

About this Structure

4m2z is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  1. Shi Z, Nicholson RH, Jaggi R, Nicholson AW. Characterization of Aquifex aeolicus ribonuclease III and the reactivity epitopes of its pre-ribosomal RNA substrates. Nucleic Acids Res. 2011 Apr;39(7):2756-68. doi: 10.1093/nar/gkq1030. Epub 2010, Dec 7. PMID:21138964 doi:http://dx.doi.org/10.1093/nar/gkq1030
  2. Gan J, Tropea JE, Austin BP, Court DL, Waugh DS, Ji X. Structural insight into the mechanism of double-stranded RNA processing by ribonuclease III. Cell. 2006 Jan 27;124(2):355-66. PMID:16439209 doi:10.1016/j.cell.2005.11.034

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