4ca8

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m (Protected "4ca8" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4ca8| PDB=4ca8 | SCENE= }}
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===Drosophila Angiotensin converting enzyme (AnCE) in complex with a phosphinic tripeptide FII===
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{{ABSTRACT_PUBMED_24289879}}
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The entry 4ca8 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/ACE_DROME ACE_DROME]] May be involved in the specific maturation or degradation of a number of bioactive peptides. May play a role in the contractions of the heart, gut and testes, and in spermatid differentiation.<ref>PMID:12591244</ref>
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Authors: Masuyer, G., Akif, M., Czarny, B., Beau, F., Schwager, S.L.U., Sturrock, E.D., Isaac, R.E., Dive, V., Acharya, K.R.
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==About this Structure==
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[[4ca8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CA8 OCA].
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Description: Drosophila Angiotensin converting enzyme (AnCE) in complex with a phosphinic tripeptide FII
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==Reference==
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<ref group="xtra">PMID:024289879</ref><references group="xtra"/><references/>
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[[Category: Peptidyl-dipeptidase A]]
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[[Category: Acharya, K R.]]
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[[Category: Akif, M.]]
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[[Category: Beau, F.]]
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[[Category: Czarny, B.]]
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[[Category: Dive, V.]]
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[[Category: Isaac, R E.]]
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[[Category: Masuyer, G.]]
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[[Category: Schwager, S L.U.]]
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[[Category: Sturrock, E D.]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor binding]]
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[[Category: Zinc metallopeptidase]]

Revision as of 13:36, 11 December 2013

Template:STRUCTURE 4ca8

Contents

Drosophila Angiotensin converting enzyme (AnCE) in complex with a phosphinic tripeptide FII

Template:ABSTRACT PUBMED 24289879

Function

[ACE_DROME] May be involved in the specific maturation or degradation of a number of bioactive peptides. May play a role in the contractions of the heart, gut and testes, and in spermatid differentiation.[1]

About this Structure

4ca8 is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Masuyer G, Akif M, Czarny B, Beau F, Schwager SL, Sturrock ED, Isaac RE, Dive V, Acharya KR. Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin-I converting enzyme. FEBS J. 2013 Nov 29. doi: 10.1111/febs.12660. PMID:24289879 doi:http://dx.doi.org/10.1111/febs.12660
  1. Hurst D, Rylett CM, Isaac RE, Shirras AD. The drosophila angiotensin-converting enzyme homologue Ance is required for spermiogenesis. Dev Biol. 2003 Feb 15;254(2):238-47. PMID:12591244

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