4nfu

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m (Protected "4nfu" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4nfu| PDB=4nfu | SCENE= }}
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===Structure of the central plant immunity signaling node EDS1 in complex with its interaction partner SAG101===
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{{ABSTRACT_PUBMED_21301097}}
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The entry 4nfu is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/SG101_ARATH SG101_ARATH]] Acyl hydrolase that triggers the leaf senescence onset. Can use triolein as substrate to produce oleic acids.<ref>PMID:11971136</ref> <ref>PMID:16040633</ref> <ref>PMID:22072959</ref> <ref>PMID:23356583</ref> Involved in the EDS1-dependent intrinsic and indispensable resistance signaling pathway; together with PAD4, required for programmed cell death triggered by RPS4 in response to avirulent pathogens (e.g. Pseudomonas syringae pv. tomato strain DC3000 and Hyaloperonospora parasitica isolates CALA2 and EMWA1) and in restricting the growth of virulent pathogens (e.g. H. parasitica isolates NOCO2 and P.syringae pv. tomato strain DC3000 avrRps4). Regulates the nuclear localization of EDS1. Essential for the RPP8/HRT-mediated resistance to the turnip crinkle virus (TCV). Involved in the post-invasion resistance to Phakopsora pachyrhizi in the mesophyll.<ref>PMID:11971136</ref> <ref>PMID:16040633</ref> <ref>PMID:22072959</ref> <ref>PMID:23356583</ref>
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Authors: WAGNER, S., STUTTMANN, J., RIETZ, S., Guerois, R., Niefind, K., Parker, J. E.
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==About this Structure==
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[[4nfu]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NFU OCA].
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Description: STRUCTURE OF THE CENTRAL PLANT IMMUNITY SIGNALING NODE EDS1 IN COMPLEX WITH ITS INTERACTION PARTNER SAG101
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==Reference==
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<ref group="xtra">PMID:021301097</ref><references group="xtra"/><references/>
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[[Category: Carboxylesterase]]
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[[Category: Guerois, R.]]
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[[Category: Niefind, K.]]
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[[Category: Parker, J E.]]
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[[Category: Rietz, S.]]
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[[Category: Stuttmann, J.]]
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[[Category: Wagner, S.]]
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[[Category: Alpha/beta hydrolase fold]]
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[[Category: Hydrolase]]
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[[Category: Innate immunity]]
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[[Category: Nucleus]]
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[[Category: Pad4]]
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[[Category: Pathogen defense]]
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[[Category: Phytoalexin deficient 4]]
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[[Category: Signaling protein]]

Revision as of 13:41, 11 December 2013

Template:STRUCTURE 4nfu

Contents

Structure of the central plant immunity signaling node EDS1 in complex with its interaction partner SAG101

Template:ABSTRACT PUBMED 21301097

Function

[SG101_ARATH] Acyl hydrolase that triggers the leaf senescence onset. Can use triolein as substrate to produce oleic acids.[1] [2] [3] [4] Involved in the EDS1-dependent intrinsic and indispensable resistance signaling pathway; together with PAD4, required for programmed cell death triggered by RPS4 in response to avirulent pathogens (e.g. Pseudomonas syringae pv. tomato strain DC3000 and Hyaloperonospora parasitica isolates CALA2 and EMWA1) and in restricting the growth of virulent pathogens (e.g. H. parasitica isolates NOCO2 and P.syringae pv. tomato strain DC3000 avrRps4). Regulates the nuclear localization of EDS1. Essential for the RPP8/HRT-mediated resistance to the turnip crinkle virus (TCV). Involved in the post-invasion resistance to Phakopsora pachyrhizi in the mesophyll.[5] [6] [7] [8]

About this Structure

4nfu is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Wagner S, Rietz S, Parker JE, Niefind K. Crystallization and preliminary crystallographic analysis of Arabidopsis thaliana EDS1, a key component of plant immunity, in complex with its signalling partner SAG101. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Feb 1;67(Pt 2):245-8. doi:, 10.1107/S1744309110051249. Epub 2011 Jan 22. PMID:21301097 doi:http://dx.doi.org/10.1107/S1744309110051249
  1. ↑ He Y, Gan S. A gene encoding an acyl hydrolase is involved in leaf senescence in Arabidopsis. Plant Cell. 2002 Apr;14(4):805-15. PMID:11971136
  2. ↑ Feys BJ, Wiermer M, Bhat RA, Moisan LJ, Medina-Escobar N, Neu C, Cabral A, Parker JE. Arabidopsis SENESCENCE-ASSOCIATED GENE101 stabilizes and signals within an ENHANCED DISEASE SUSCEPTIBILITY1 complex in plant innate immunity. Plant Cell. 2005 Sep;17(9):2601-13. Epub 2005 Jul 22. PMID:16040633 doi:http://dx.doi.org/tpc.105.033910
  3. ↑ Zhu S, Jeong RD, Venugopal SC, Lapchyk L, Navarre D, Kachroo A, Kachroo P. SAG101 forms a ternary complex with EDS1 and PAD4 and is required for resistance signaling against turnip crinkle virus. PLoS Pathog. 2011 Nov;7(11):e1002318. doi: 10.1371/journal.ppat.1002318. Epub, 2011 Nov 3. PMID:22072959 doi:http://dx.doi.org/10.1371/journal.ppat.1002318
  4. ↑ Langenbach C, Campe R, Schaffrath U, Goellner K, Conrath U. UDP-glucosyltransferase UGT84A2/BRT1 is required for Arabidopsis nonhost resistance to the Asian soybean rust pathogen Phakopsora pachyrhizi. New Phytol. 2013 Apr;198(2):536-45. doi: 10.1111/nph.12155. Epub 2013 Jan 29. PMID:23356583 doi:http://dx.doi.org/10.1111/nph.12155
  5. ↑ He Y, Gan S. A gene encoding an acyl hydrolase is involved in leaf senescence in Arabidopsis. Plant Cell. 2002 Apr;14(4):805-15. PMID:11971136
  6. ↑ Feys BJ, Wiermer M, Bhat RA, Moisan LJ, Medina-Escobar N, Neu C, Cabral A, Parker JE. Arabidopsis SENESCENCE-ASSOCIATED GENE101 stabilizes and signals within an ENHANCED DISEASE SUSCEPTIBILITY1 complex in plant innate immunity. Plant Cell. 2005 Sep;17(9):2601-13. Epub 2005 Jul 22. PMID:16040633 doi:http://dx.doi.org/tpc.105.033910
  7. ↑ Zhu S, Jeong RD, Venugopal SC, Lapchyk L, Navarre D, Kachroo A, Kachroo P. SAG101 forms a ternary complex with EDS1 and PAD4 and is required for resistance signaling against turnip crinkle virus. PLoS Pathog. 2011 Nov;7(11):e1002318. doi: 10.1371/journal.ppat.1002318. Epub, 2011 Nov 3. PMID:22072959 doi:http://dx.doi.org/10.1371/journal.ppat.1002318
  8. ↑ Langenbach C, Campe R, Schaffrath U, Goellner K, Conrath U. UDP-glucosyltransferase UGT84A2/BRT1 is required for Arabidopsis nonhost resistance to the Asian soybean rust pathogen Phakopsora pachyrhizi. New Phytol. 2013 Apr;198(2):536-45. doi: 10.1111/nph.12155. Epub 2013 Jan 29. PMID:23356583 doi:http://dx.doi.org/10.1111/nph.12155

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