4i3p

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'''Unreleased structure'''
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{{STRUCTURE_4i3p| PDB=4i3p | SCENE= }}
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===1.96 angstrom x-ray crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase bound with 3-aminosalicylic acid from cupraavidus metallidurans===
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The entry 4i3p is ON HOLD until 00 0001
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==Function==
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[[http://www.uniprot.org/uniprot/3HAO_RALME 3HAO_RALME]] Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.<ref>PMID:15909977</ref>
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Authors: Liu, F, Liu, A
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==About this Structure==
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[[4i3p]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I3P OCA].
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Description: 1.96 angstrom x-ray crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase bound with 3-aminosalicylic acid from cupraavidus metallidurans
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==Reference==
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<references group="xtra"/><references/>
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[[Category: 3-hydroxyanthranilate 3,4-dioxygenase]]
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[[Category: Liu, A.]]
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[[Category: Liu, F.]]
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[[Category: Bi-cupin iron-binding]]
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[[Category: Dioxygenase]]
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[[Category: Oxioreductase-substrate complex]]

Revision as of 13:46, 11 December 2013

Template:STRUCTURE 4i3p

Contents

1.96 angstrom x-ray crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase bound with 3-aminosalicylic acid from cupraavidus metallidurans

Function

[3HAO_RALME] Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.[1]

About this Structure

4i3p is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  1. Colabroy KL, Zhai H, Li T, Ge Y, Zhang Y, Liu A, Ealick SE, McLafferty FW, Begley TP. The mechanism of inactivation of 3-hydroxyanthranilate-3,4-dioxygenase by 4-chloro-3-hydroxyanthranilate. Biochemistry. 2005 May 31;44(21):7623-31. PMID:15909977 doi:http://dx.doi.org/10.1021/bi0473455

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