UDP-galactose 4-epimerase (GalE) reversibly converts UDP-galactose to UDP-glucose. GalE catalyzes the last step in galactose metabolism. GalE uses NAD+ as a cofactor.
3D structures of UDP-galactose 4 epimerase
Updated on 12-December-2013
GalE with no ligand
1ek5 - hGalE + NAD - human
2c20 - GalE + NAD – Bacillus anthracis
2p5u, 2p5y - GalE + NAD – Thermus thermophilus
3enk - GalE + NAD – Burkholderia pseudo mallei
GalE complexes
1nah, 1nai – EcGalE + NAD + UDP – Escherichia coli
1gy8 - EcGalE (mutant) + NAD + UDP
1xel, 1udb, 1a9y - EcGalE + NAD + UDP-glucose
1a9z, 1lrl - EcGalE (mutant) + NAD + UDP-glucose
1uda - EcGalE + NAD + UDP-galactose
1lrj - EcGalE + NAD + UDP-acetylglucosamine
1lrj, 1lrk - EcGalE (mutant) + NAD + UDP-acetylglucosamine
1udc - EcGalE + NAD + UDP-mannose
1kvr, 1kvs, 1kvt, [[1kvsu], 1kvq – EcGalE (mutant) + NAD + UDP-phenol
2udp - EcGalE + NAD + UDP-phenol
1ek6 - hGalE + NAD + UDP-glucose
1hzj - hGalE + NAD + UDP-glucosamine
1i3k - hGalE (mutant) + NAD + UDP-glucose
1i3l, 2cnb - hGalE (mutant) + NAD + UDP-galactose
1i3m, 1i3n - hGalE (mutant) + NAD + UDP-acetylglucosamine
