C-X-C motif chemokine

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: {{STRUCTURE_1qg7|right| PDB=1qg7 | SCENE= |CAPTION=CXCL12α dimer complex with sulfate, 1qg7 }} '''C-X-C motif chemokine''' (CXCL) are small chemokines.<br /> • CXCL10 or IP-10...)
Line 1: Line 1:
- 
{{STRUCTURE_1qg7|right| PDB=1qg7 | SCENE= |CAPTION=CXCL12α dimer complex with sulfate, [[1qg7]] }}
{{STRUCTURE_1qg7|right| PDB=1qg7 | SCENE= |CAPTION=CXCL12α dimer complex with sulfate, [[1qg7]] }}
'''C-X-C motif chemokine''' (CXCL) are small chemokines.<br />
'''C-X-C motif chemokine''' (CXCL) are small chemokines.<br />
-
• CXCL10 or IP-10 or interferon γ-induced protein 10 acts as chemoattractant for monocytes, T cells NK cells and dendritic cells. CXCL10 binds to the cell surface receptor CXCR3.<br />
+
'''CXCL10''' or '''IP-10''' or '''interferon γ-induced protein 10''' acts as chemoattractant for monocytes, T cells NK cells and dendritic cells. CXCL10 binds to the cell surface receptor CXCR3.<br />
-
• CXCL11 or IP-9 or interferon γ-induced protein 9 acts as chemotactic for activated T cells.<br />
+
'''CXCL11''' or '''IP-9''' or '''interferon γ-induced protein 9''' acts as chemotactic for activated T cells.<br />
-
• CXCL12 or Stromal-Derived-Factor-1 (SDF1) has a role in angiogenesis, tumor metastasis and the migration of cells from the liver to the bone marrow during embryogenesis.<br />
+
'''CXCL12''' or '''Stromal-Derived-Factor-1''' (SDF1) has a role in angiogenesis, tumor metastasis and the migration of cells from the liver to the bone marrow during embryogenesis.<br />
-
• CXCL14 or BRAK acts as chemotactic for monocytes and inhibits angiogenesis.<br />
+
'''CXCL14''' or '''BRAK''' acts as chemotactic for monocytes and inhibits angiogenesis.<br />
== 3D Structures of C-X-C motif chemokine ==
== 3D Structures of C-X-C motif chemokine ==

Revision as of 12:07, 16 December 2013

PDB ID 1qg7

Drag the structure with the mouse to rotate
CXCL12α dimer complex with sulfate, 1qg7
Ligands:
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



C-X-C motif chemokine (CXCL) are small chemokines.
CXCL10 or IP-10 or interferon γ-induced protein 10 acts as chemoattractant for monocytes, T cells NK cells and dendritic cells. CXCL10 binds to the cell surface receptor CXCR3.
CXCL11 or IP-9 or interferon γ-induced protein 9 acts as chemotactic for activated T cells.
CXCL12 or Stromal-Derived-Factor-1 (SDF1) has a role in angiogenesis, tumor metastasis and the migration of cells from the liver to the bone marrow during embryogenesis.
CXCL14 or BRAK acts as chemotactic for monocytes and inhibits angiogenesis.

Contents

3D Structures of C-X-C motif chemokine

Updated on 16-December-2013

CXCL10

1lv9 – hCXCL – human – NMR
1o7z, 1o7y, 1o80 – hCXCL
2r3z – CXCL – mouse

CXCL11

1rjt – hCXCL

CXCL12

3D Structures of Stromal Derived Factor 1

Updated on 16-December-2013

2kec, 2ked, 2kee, 2sdf, 1sdf, 1vmc - hSDF1α – NMR - human
1qg7, 3hp3 - hSDF1α
2k0l, 2k01, 2kol – hSDF1α (mutant) – NMR
1a15, 3gv3 - hSDF1α (mutant)
2nwg - hSDF1α+heparin
2j7z - hSDF1α residues 22-89
2k03, 2k04, 2k05 - hSDF1α (mutant)+ hCXCR4 N-terminal (mutant)

CXCL14

2hdl – hCXCL – NMR

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

Personal tools