4lx1
From Proteopedia
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{{STRUCTURE_4lx1| PDB=4lx1 | SCENE= }} | {{STRUCTURE_4lx1| PDB=4lx1 | SCENE= }} | ||
===Crystal structure of Myo5a globular tail domain=== | ===Crystal structure of Myo5a globular tail domain=== | ||
| + | {{ABSTRACT_PUBMED_24248336}} | ||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
| - | [[4lx1]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LX1 OCA]. | + | [[4lx1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LX1 OCA]. |
==Reference== | ==Reference== | ||
| - | <references group="xtra"/><references/> | + | <ref group="xtra">PMID:024248336</ref><references group="xtra"/><references/> |
| + | [[Category: Human]] | ||
[[Category: Attanda, W.]] | [[Category: Attanda, W.]] | ||
[[Category: Coulibaly, D.]] | [[Category: Coulibaly, D.]] | ||
Revision as of 07:41, 18 December 2013
Contents |
Crystal structure of Myo5a globular tail domain
Template:ABSTRACT PUBMED 24248336
Disease
[MYO5A_HUMAN] Griscelli disease type 3;Neuroectodermal melanolysosomal disease;Griscelli disease type 1. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
Function
[MYO5A_HUMAN] Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.[1]
About this Structure
4lx1 is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA.
Reference
- Pylypenko O, Attanda W, Gauquelin C, Lahmani M, Coulibaly D, Baron B, Hoos S, Titus MA, England P, Houdusse AM. Structural basis of myosin V Rab GTPase-dependent cargo recognition. Proc Natl Acad Sci U S A. 2013 Nov 18. PMID:24248336 doi:http://dx.doi.org/10.1073/pnas.1314329110
- ↑ Mehta AD, Rock RS, Rief M, Spudich JA, Mooseker MS, Cheney RE. Myosin-V is a processive actin-based motor. Nature. 1999 Aug 5;400(6744):590-3. PMID:10448864 doi:http://dx.doi.org/10.1038/23072
