2tmk
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="2tmk" size="450" color="white" frame="true" align="right" spinBox="true" caption="2tmk, resolution 2.4Å" /> '''YEAST THYMIDYLATE KIN...) |
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| - | [[Image:2tmk.jpg|left|200px]]<br /><applet load="2tmk" size=" | + | [[Image:2tmk.jpg|left|200px]]<br /><applet load="2tmk" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="2tmk, resolution 2.4Å" /> | caption="2tmk, resolution 2.4Å" /> | ||
'''YEAST THYMIDYLATE KINASE COMPLEXED WITH 3'-AZIDO-3'-DEOXYTHYMIDINE MONOPHOSPHATE (AZT-MP)'''<br /> | '''YEAST THYMIDYLATE KINASE COMPLEXED WITH 3'-AZIDO-3'-DEOXYTHYMIDINE MONOPHOSPHATE (AZT-MP)'''<br /> | ||
==About this Structure== | ==About this Structure== | ||
| - | 2TMK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with SO4 and ATM as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] Full crystallographic information is available from [http:// | + | 2TMK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=ATM:'>ATM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2TMK OCA]. |
==Reference== | ==Reference== | ||
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[[Category: transferase (phosphotransferase)]] | [[Category: transferase (phosphotransferase)]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:49:49 2008'' |
Revision as of 16:49, 21 February 2008
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YEAST THYMIDYLATE KINASE COMPLEXED WITH 3'-AZIDO-3'-DEOXYTHYMIDINE MONOPHOSPHATE (AZT-MP)
About this Structure
2TMK is a Single protein structure of sequence from Saccharomyces cerevisiae with and as ligands. Active as dTMP kinase, with EC number 2.7.4.9 Full crystallographic information is available from OCA.
Reference
Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation., Lavie A, Vetter IR, Konrad M, Goody RS, Reinstein J, Schlichting I, Nat Struct Biol. 1997 Aug;4(8):601-4. PMID:9253404
Page seeded by OCA on Thu Feb 21 18:49:49 2008
