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4lim

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_4lim| PDB=4lim | SCENE= }}
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===Crystal structure of the catalytic subunit of yeast primase===
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{{ABSTRACT_PUBMED_24239947}}
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The entry 4lim is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/PRI1_YEAST PRI1_YEAST]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. In a complex with DNA polymerase alpha (DNA polymerase alpha:primase) constitutes a replicative polymerase. Both primase components participate in formation of the active center, but the ATP-binding site is exclusively located on p48.
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Authors: Vaithiyalingam, S., Chazin, W.J., Berger, J.M., Corn, J., Stephenson, S.
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==About this Structure==
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[[4lim]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LIM OCA].
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Description: Crystal structure of the catalytic subunit of yeast primase
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==Reference==
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<ref group="xtra">PMID:024239947</ref><references group="xtra"/><references/>
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[[Category: Berger, J M.]]
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[[Category: Chazin, W J.]]
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[[Category: Corn, J.]]
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[[Category: Stephenson, S.]]
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[[Category: Vaithiyalingam, S.]]
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[[Category: Prim fold]]
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[[Category: Transferase]]

Revision as of 10:23, 18 December 2013

Template:STRUCTURE 4lim

Contents

Crystal structure of the catalytic subunit of yeast primase

Template:ABSTRACT PUBMED 24239947

Function

[PRI1_YEAST] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. In a complex with DNA polymerase alpha (DNA polymerase alpha:primase) constitutes a replicative polymerase. Both primase components participate in formation of the active center, but the ATP-binding site is exclusively located on p48.

About this Structure

4lim is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Vaithiyalingam S, Arnett DR, Aggarwal A, Eichman BF, Fanning E, Chazin WJ. Insights into Eukaryotic Primer Synthesis from Structures of the p48 Subunit of Human DNA Primase. J Mol Biol. 2013 Nov 13. pii: S0022-2836(13)00718-3. doi:, 10.1016/j.jmb.2013.11.007. PMID:24239947 doi:http://dx.doi.org/10.1016/j.jmb.2013.11.007

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