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4nab

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_4nab| PDB=4nab | SCENE= }}
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===Structure of the (SR)Ca2+-ATPase mutant E309Q in the Ca2-E1-MgAMPPCP form===
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{{ABSTRACT_PUBMED_24270570}}
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The entry 4nab is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT]] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).
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Authors: Bublitz, M., Clausen, J.D., Arnou, B., Montigny, C., Jaxel, C., Nissen, P., Mueller, J.V., Andersen, J.P., le Maire, M.
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==About this Structure==
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[[4nab]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NAB OCA].
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Description: Structure of the (SR)Ca2+-ATPase mutant E309Q in the Ca2-E1-MgAMPPCP form
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==Reference==
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<ref group="xtra">PMID:024270570</ref><references group="xtra"/><references/>
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[[Category: Calcium-transporting ATPase]]
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[[Category: Andersen, J P.]]
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[[Category: Arnou, B.]]
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[[Category: Bublitz, M.]]
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[[Category: Clausen, J D.]]
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[[Category: Jaxel, C.]]
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[[Category: Maire, M le.]]
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[[Category: Montigny, C.]]
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[[Category: Mueller, J V.]]
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[[Category: Nissen, P.]]
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[[Category: Calcium-transporting atpase]]
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[[Category: Hydrolase]]
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[[Category: Mutant e309q]]
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[[Category: P-type atpase]]
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[[Category: Sarcoplasmic reticulum]]

Revision as of 10:27, 18 December 2013

Template:STRUCTURE 4nab

Contents

Structure of the (SR)Ca2+-ATPase mutant E309Q in the Ca2-E1-MgAMPPCP form

Template:ABSTRACT PUBMED 24270570

Function

[AT2A1_RABIT] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).

About this Structure

4nab is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Clausen JD, Bublitz M, Arnou B, Montigny C, Jaxel C, Moller JV, Nissen P, Andersen JP, le Maire M. SERCA mutant E309Q binds two Ca(2+) ions but adopts a catalytically incompetent conformation. EMBO J. 2013 Dec 11;32(24):3231-43. doi: 10.1038/emboj.2013.250. Epub 2013 Nov, 22. PMID:24270570 doi:http://dx.doi.org/10.1038/emboj.2013.250

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OCA

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