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Stimulator of interferon genes
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'''Stimulator of interferon genes''' (STING) induces production of type I interferon when cells are infected by viruses, mycobacteria and intracellular parasites. STING recognizes and binds cyclic-di-GMP produced by bacteria and cyclic-GMP AMP (cGAMP) produced by viruses. The C-terminal domain (CTD) (residues 139-379 in human) of STING binds cyclic-di-GMP. STING is a facilitator of innate immune signaling. | '''Stimulator of interferon genes''' (STING) induces production of type I interferon when cells are infected by viruses, mycobacteria and intracellular parasites. STING recognizes and binds cyclic-di-GMP produced by bacteria and cyclic-GMP AMP (cGAMP) produced by viruses. The C-terminal domain (CTD) (residues 139-379 in human) of STING binds cyclic-di-GMP. STING is a facilitator of innate immune signaling. | ||
Revision as of 11:05, 18 December 2013
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