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1usy
From Proteopedia
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| - | [[Image:1usy.png|left|200px]] | ||
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{{STRUCTURE_1usy| PDB=1usy | SCENE= }} | {{STRUCTURE_1usy| PDB=1usy | SCENE= }} | ||
| + | ===ATP phosphoribosyl transferase (HisG:HisZ) complex from Thermotoga maritima=== | ||
| + | {{ABSTRACT_PUBMED_15660995}} | ||
| - | ===ATP | + | ==Function== |
| - | + | [[http://www.uniprot.org/uniprot/HIS1_THEMA HIS1_THEMA]] Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity). [[http://www.uniprot.org/uniprot/HISZ_THEMA HISZ_THEMA]] Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity). | |
| - | + | ||
==About this Structure== | ==About this Structure== | ||
| - | [[1usy]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[1usy]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Thema Thema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1USY OCA]. |
==See Also== | ==See Also== | ||
*[[ATP Phosphoribosyl Transferase|ATP Phosphoribosyl Transferase]] | *[[ATP Phosphoribosyl Transferase|ATP Phosphoribosyl Transferase]] | ||
| + | *[[Phosphoribosyltransferase|Phosphoribosyltransferase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:015660995</ref><references group="xtra"/> | + | <ref group="xtra">PMID:015660995</ref><references group="xtra"/><references/> |
[[Category: ATP phosphoribosyltransferase]] | [[Category: ATP phosphoribosyltransferase]] | ||
| - | [[Category: | + | [[Category: Thema]] |
[[Category: Fernandez, F J.]] | [[Category: Fernandez, F J.]] | ||
[[Category: Murphy, G E.]] | [[Category: Murphy, G E.]] | ||
Revision as of 08:40, 25 December 2013
Contents |
ATP phosphoribosyl transferase (HisG:HisZ) complex from Thermotoga maritima
Template:ABSTRACT PUBMED 15660995
Function
[HIS1_THEMA] Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity). [HISZ_THEMA] Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity).
About this Structure
1usy is a 8 chain structure with sequence from Thema. Full crystallographic information is available from OCA.
See Also
Reference
- Vega MC, Zou P, Fernandez FJ, Murphy GE, Sterner R, Popov A, Wilmanns M. Regulation of the hetero-octameric ATP phosphoribosyl transferase complex from Thermotoga maritima by a tRNA synthetase-like subunit. Mol Microbiol. 2005 Feb;55(3):675-86. PMID:15660995 doi:http://dx.doi.org/10.1111/j.1365-2958.2004.04422.x
