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4la5
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[4la5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[4la5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strco Strco]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LA5 OCA]. |
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:023844678</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:023844678</ref><references group="xtra"/><references/> | ||
[[Category: 2-methylisoborneol synthase]] | [[Category: 2-methylisoborneol synthase]] | ||
| + | [[Category: Strco]] | ||
[[Category: Christianson, D W.]] | [[Category: Christianson, D W.]] | ||
[[Category: Koksal, M.]] | [[Category: Koksal, M.]] | ||
Revision as of 08:52, 25 December 2013
Contents |
Crystal structure of 2-methylisoborneol synthase from Streptomyces coelicolor A3(2)
Template:ABSTRACT PUBMED 23844678
Function
[MIBS_STRCO] Catalyzes the cyclization of 2-methylgeranyl diphosphate (2-MeGPP) to 2-methylisoborneol (2-MIB), which likely involves the intermediacy of 2-methyllinalyl diphosphate. Is also able to catalyze the cyclization of geranyl diphosphate (GPP), albeit with much lower efficiency, leading to the formation of a complex mixture of cyclic monoterpenes, consisting of alpha-pinene (6%), beta-pinene (23%), limonene (32%), gamma-terpinene (29%), and delta-terpinene (10%).
About this Structure
4la5 is a 1 chain structure with sequence from Strco. Full crystallographic information is available from OCA.
Reference
- Koksal M, Chou WK, Cane DE, Christianson DW. Unexpected Reactivity of 2-Fluorolinalyl Diphosphate in the Active Site of Crystalline 2-Methylisoborneol Synthase. Biochemistry. 2013 Jul 22. PMID:23844678 doi:10.1021/bi400797c
