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3wam
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_3wam| PDB=3wam | SCENE= }} | |
| + | ===Crystal structure of human LC3C_8-125=== | ||
| + | {{ABSTRACT_PUBMED_24290141}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/MLP3C_HUMAN MLP3C_HUMAN]] Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruites all ATG8 family members to infecting bacteria such as S.Typhimurium.<ref>PMID:23022382</ref> | ||
| - | + | ==About this Structure== | |
| + | [[3wam]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WAM OCA]. | ||
| - | + | ==Reference== | |
| + | <ref group="xtra">PMID:024290141</ref><references group="xtra"/><references/> | ||
| + | [[Category: Dobson, R C.J.]] | ||
| + | [[Category: Kato, R.]] | ||
| + | [[Category: Kawasaki, M.]] | ||
| + | [[Category: Morita, E.]] | ||
| + | [[Category: Suzuki, H.]] | ||
| + | [[Category: Tabata, K.]] | ||
| + | [[Category: Wakatsuki, S.]] | ||
| + | [[Category: Yoshimori, T.]] | ||
| + | [[Category: Autophagy]] | ||
| + | [[Category: Protein transport]] | ||
| + | [[Category: Ubiquitin-like fold]] | ||
Revision as of 10:19, 25 December 2013
Contents |
Crystal structure of human LC3C_8-125
Template:ABSTRACT PUBMED 24290141
Function
[MLP3C_HUMAN] Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruites all ATG8 family members to infecting bacteria such as S.Typhimurium.[1]
About this Structure
3wam is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- Suzuki H, Tabata K, Morita E, Kawasaki M, Kato R, Dobson RC, Yoshimori T, Wakatsuki S. Structural Basis of the Autophagy-Related LC3/Atg13 LIR Complex: Recognition and Interaction Mechanism. Structure. 2013 Nov 25. pii: S0969-2126(13)00401-2. doi:, 10.1016/j.str.2013.09.023. PMID:24290141 doi:http://dx.doi.org/10.1016/j.str.2013.09.023
- ↑ von Muhlinen N, Akutsu M, Ravenhill BJ, Foeglein A, Bloor S, Rutherford TJ, Freund SM, Komander D, Randow F. LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy. Mol Cell. 2012 Nov 9;48(3):329-42. doi: 10.1016/j.molcel.2012.08.024. Epub 2012, Sep 27. PMID:23022382 doi:http://dx.doi.org/10.1016/j.molcel.2012.08.024
