This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4h80

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "4h80" [edit=sysop:move=sysop])
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_4h80| PDB=4h80 | SCENE= }}
 +
===Crystal structure of human ALDH3A1 with its isozyme selective inhibitor - N-[4-(4-methylsulfonyl-2-nitroanilino)phenyl]acetamide===
-
The entry 4h80 is ON HOLD
+
==Function==
 +
[[http://www.uniprot.org/uniprot/AL3A1_HUMAN AL3A1_HUMAN]] ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.
-
Authors: Hurley, T.D., Parajuli, B.
+
==About this Structure==
-
 
+
[[4h80]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H80 OCA].
-
Description: Crystal structure of human ALDH3A1 with its isozyme selective inhibitor -N-[4-(4-methylsulfonyl-2-nitroanilino)phenyl]acetamide
+
[[Category: Hurley, T D.]]
 +
[[Category: Parajuli, B.]]
 +
[[Category: Catalyzes benzaldehyde]]
 +
[[Category: Dehydrogenase]]
 +
[[Category: Nadp+ binding]]
 +
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
 +
[[Category: Rossman fold]]

Revision as of 10:24, 25 December 2013

Template:STRUCTURE 4h80

Crystal structure of human ALDH3A1 with its isozyme selective inhibitor - N-[4-(4-methylsulfonyl-2-nitroanilino)phenyl]acetamide

Function

[AL3A1_HUMAN] ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.

About this Structure

4h80 is a 8 chain structure. Full crystallographic information is available from OCA.

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4h80"
Personal tools