4keh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_4keh| PDB=4keh | SCENE= }}
 +
===Crosslinked Crystal Structure of Type II Fatty Synthase Dehydratase, FabA, and Acyl Carrier Protein, AcpP===
-
The entry 4keh is ON HOLD
+
==Function==
 +
[[http://www.uniprot.org/uniprot/FABA_ECOLI FABA_ECOLI]] Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. Is inactive in the dehydration of long chain unsaturated beta-hydroxyacyl-ACP.<ref>PMID:8910376</ref> [[http://www.uniprot.org/uniprot/K0BL73_ECO1E K0BL73_ECO1E]] Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity).[RuleBase:RU003545][HAMAP-Rule:MF_01217]
-
Authors: Nguyen, C., Haushalter, R., Finzel, K., Leong, J., Le, B.C., Burkart, M., Tsai, S.C.
+
==About this Structure==
 +
[[4keh]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEH OCA].
-
Description: Crosslinked Crystal Structure of Type II Fatty Synthase Dehydratase, FabA, and Acyl Carrier Protein, AcpP
+
==Reference==
 +
<references group="xtra"/><references/>
 +
[[Category: Burkart, M.]]
 +
[[Category: Finzel, K.]]
 +
[[Category: Haushalter, R.]]
 +
[[Category: Le, B C.]]
 +
[[Category: Leong, J.]]
 +
[[Category: Nguyen, C.]]
 +
[[Category: Tsai, S C.]]
 +
[[Category: Acyl carrier protein]]
 +
[[Category: Dehydratase/isomerase]]
 +
[[Category: Fatty acid synthesis]]
 +
[[Category: Isomerase-biosynthetic protein complex]]
 +
[[Category: Protein-protein complex]]

Revision as of 10:26, 25 December 2013

Template:STRUCTURE 4keh

Contents

Crosslinked Crystal Structure of Type II Fatty Synthase Dehydratase, FabA, and Acyl Carrier Protein, AcpP

Function

[FABA_ECOLI] Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. Is inactive in the dehydration of long chain unsaturated beta-hydroxyacyl-ACP.[1] [K0BL73_ECO1E] Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity).[RuleBase:RU003545][HAMAP-Rule:MF_01217]

About this Structure

4keh is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Heath RJ, Rock CO. Roles of the FabA and FabZ beta-hydroxyacyl-acyl carrier protein dehydratases in Escherichia coli fatty acid biosynthesis. J Biol Chem. 1996 Nov 1;271(44):27795-801. PMID:8910376

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4keh"
Personal tools