4m2p

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{{STRUCTURE_4m2p| PDB=4m2p | SCENE= }}
{{STRUCTURE_4m2p| PDB=4m2p | SCENE= }}
===Crystal structure of a non-myristoylated C39D recoverin mutant with one calcium ion bound to EF-hand 3===
===Crystal structure of a non-myristoylated C39D recoverin mutant with one calcium ion bound to EF-hand 3===
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{{ABSTRACT_PUBMED_24189072}}
==Function==
==Function==
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==About this Structure==
==About this Structure==
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[[4m2p]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M2P OCA].
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[[4m2p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M2P OCA].
==Reference==
==Reference==
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<references group="xtra"/><references/>
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<ref group="xtra">PMID:024189072</ref><references group="xtra"/><references/>
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[[Category: Bovin]]
[[Category: Kumar, R Prem.]]
[[Category: Kumar, R Prem.]]
[[Category: Oprian, D D.]]
[[Category: Oprian, D D.]]

Revision as of 10:43, 1 January 2014

Template:STRUCTURE 4m2p

Contents

Crystal structure of a non-myristoylated C39D recoverin mutant with one calcium ion bound to EF-hand 3

Template:ABSTRACT PUBMED 24189072

Function

[RECO_BOVIN] Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.[1] [2]

About this Structure

4m2p is a 1 chain structure with sequence from Bovin. Full crystallographic information is available from OCA.

Reference

  • Ranaghan MJ, Kumar RP, Chakrabarti KS, Buosi V, Kern D, Oprian DD. A Highly Conserved Cysteine of Neuronal Calcium-sensing Proteins Controls Cooperative Binding of Ca2+ to Recoverin. J Biol Chem. 2013 Dec 13;288(50):36160-7. doi: 10.1074/jbc.M113.524355. Epub 2013, Nov 4. PMID:24189072 doi:http://dx.doi.org/10.1074/jbc.M113.524355
  1. ↑ Hurley JB, Dizhoor AM, Ray S, Stryer L. Recoverin's role: conclusion withdrawn. Science. 1993 May 7;260(5109):740. PMID:8097896
  2. ↑ Kawamura S, Hisatomi O, Kayada S, Tokunaga F, Kuo CH. Recoverin has S-modulin activity in frog rods. J Biol Chem. 1993 Jul 15;268(20):14579-82. PMID:8392055

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