4mz1

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m (Protected "4mz1" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4mz1| PDB=4mz1 | SCENE= }}
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===Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound P12===
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The entry 4mz1 is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/Q0P9J4_CAMJE Q0P9J4_CAMJE]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]
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Authors: Kim, Y., Makowska-Grzyska, M., Gu, M., Anderson, W.F., Joachimiak, A., Csgid, Center for Structural Genomics of Infectious Diseases (CSGID)
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==About this Structure==
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[[4mz1]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MZ1 OCA].
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Description: Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound P12
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[[Category: IMP dehydrogenase]]
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[[Category: Anderson, W F.]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Csgid]]
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[[Category: Gu, M.]]
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[[Category: Joachimiak, A.]]
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[[Category: Kim, Y.]]
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[[Category: Makowska-Grzyska, M.]]
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[[Category: Alpha-beta structure]]
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[[Category: Center for structural genomics of infectious disease]]
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[[Category: Csgid]]
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[[Category: National institute of allergy and infectious disease]]
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[[Category: Niaid]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
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[[Category: Structural genomic]]
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[[Category: Tim barrel]]

Revision as of 12:15, 1 January 2014

Template:STRUCTURE 4mz1

Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound P12

Function

[Q0P9J4_CAMJE] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]

About this Structure

4mz1 is a 3 chain structure. Full crystallographic information is available from OCA.

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OCA

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