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4mz1
From Proteopedia
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| - | ' | + | {{STRUCTURE_4mz1| PDB=4mz1 | SCENE= }} |
| + | ===Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound P12=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/Q0P9J4_CAMJE Q0P9J4_CAMJE]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964] | ||
| - | + | ==About this Structure== | |
| - | + | [[4mz1]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MZ1 OCA]. | |
| - | + | [[Category: IMP dehydrogenase]] | |
| + | [[Category: Anderson, W F.]] | ||
| + | [[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]] | ||
| + | [[Category: Csgid]] | ||
| + | [[Category: Gu, M.]] | ||
| + | [[Category: Joachimiak, A.]] | ||
| + | [[Category: Kim, Y.]] | ||
| + | [[Category: Makowska-Grzyska, M.]] | ||
| + | [[Category: Alpha-beta structure]] | ||
| + | [[Category: Center for structural genomics of infectious disease]] | ||
| + | [[Category: Csgid]] | ||
| + | [[Category: National institute of allergy and infectious disease]] | ||
| + | [[Category: Niaid]] | ||
| + | [[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Tim barrel]] | ||
Revision as of 12:15, 1 January 2014
Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound P12
Function
[Q0P9J4_CAMJE] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]
About this Structure
4mz1 is a 3 chain structure. Full crystallographic information is available from OCA.
Categories: IMP dehydrogenase | Anderson, W F. | CSGID, Center for Structural Genomics of Infectious Diseases. | Csgid | Gu, M. | Joachimiak, A. | Kim, Y. | Makowska-Grzyska, M. | Alpha-beta structure | Center for structural genomics of infectious disease | National institute of allergy and infectious disease | Niaid | Oxidoreductase-oxidoreductase inhibitor complex | Structural genomic | Tim barrel
