Tryptase
From Proteopedia
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- | {{STRUCTURE_2zeb| PDB=2zeb | SIZE=400| SCENE= |right|CAPTION=Human tryptase β-2 tetramer complex with inhibitor, [[2zeb]] }} | + | {{STRUCTURE_2zeb| PDB=2zeb | SIZE=400| SCENE= |right|CAPTION=Human tryptase β-2 tetramer complex with piperidine derivative inhibitor, [[2zeb]] }} |
'''Tryptase''' (TRP) is a serine protease found in mast cells. TRP is used as a marker for mast cell activation. | '''Tryptase''' (TRP) is a serine protease found in mast cells. TRP is used as a marker for mast cell activation. |
Revision as of 11:26, 2 January 2014
Tryptase (TRP) is a serine protease found in mast cells. TRP is used as a marker for mast cell activation.
3D Structures of tryptase
Updated on 02-January-2014
1lto – hTRP-α1 - human
2f9o - hTRP-α1 (mutant)
Tryptase complex with inhibitor
1a0l – hTRP-β + APPA
2f9n, 2f9p - hTRP-α1 (mutant) + leupeptin
2bm2, 2fww - hTRP-β2 + piperidine derivative
4a6l - hTRP-α/β1 + piperidine derivative
2fxr - hTRP-β2 + ketone inhibitor
2fpz - hTRP-β2 + benzimidazole inhibitor
2fs9, 2fs8, 2gdd, 2za5, 2zeb, 2zec - hTRP-β2 + inhibitor
3v7t - hTRP-β2 + tropanylamide inhibitor