4fxd

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{{STRUCTURE_4fxd| PDB=4fxd | SCENE= }}
{{STRUCTURE_4fxd| PDB=4fxd | SCENE= }}
===Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA===
===Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA===
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{{ABSTRACT_PUBMED_23599895}}
==Function==
==Function==
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==About this Structure==
==About this Structure==
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[[4fxd]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FXD OCA].
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[[4fxd]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FXD OCA].
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==See Also==
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*[[DNA polymerase|DNA polymerase]]
==Reference==
==Reference==
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<references group="xtra"/><references/>
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<ref group="xtra">PMID:023599895</ref><references group="xtra"/><references/>
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[[Category: Baker's yeast]]
[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
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[[Category: Saccharomyces cerevisiae s288c]]
 
[[Category: Kilkenny, M L.]]
[[Category: Kilkenny, M L.]]
[[Category: Klinge, S.]]
[[Category: Klinge, S.]]

Revision as of 07:14, 15 January 2014

Template:STRUCTURE 4fxd

Contents

Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA

Template:ABSTRACT PUBMED 23599895

Function

[DPOA_YEAST] Catalytic component of DNA polymerase alpha, which in complex with DNA primase (DNA polymerase alpha:primase) consitutes a replicative polymerase. POL1 has a role in promoting telomere replication during interaction with CDC13.[1]

About this Structure

4fxd is a 6 chain structure with sequence from Baker's yeast. Full crystallographic information is available from OCA.

See Also

Reference

  • Perera RL, Torella R, Klinge S, Kilkenny ML, Maman JD, Pellegrini L. Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha. Elife. 2013 Apr 2;2:e00482. doi: 10.7554/eLife.00482. Print 2013. PMID:23599895 doi:http://dx.doi.org/10.7554/eLife.00482
  1. ↑ Qi H, Zakian VA. The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein. Genes Dev. 2000 Jul 15;14(14):1777-88. PMID:10898792

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