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4dwq

From Proteopedia

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[[Image:4dwq.png|left|200px]]
 
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{{STRUCTURE_4dwq| PDB=4dwq | SCENE= }}
{{STRUCTURE_4dwq| PDB=4dwq | SCENE= }}
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===RNA ligase RtcB-GMP/Mn(2+) complex===
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{{ABSTRACT_PUBMED_22949672}}
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===RtcB-GMP/Mn2+ complex===
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==Function==
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[[http://www.uniprot.org/uniprot/RTCB_PYRHO RTCB_PYRHO]] tRNA-splicing ligase that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as a RNA ligase with broad substrate specificity, and may function toward other RNAs (By similarity).
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{{ABSTRACT_PUBMED_22949672}}
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==About this Structure==
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[[4dwq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/'pyrococcus_shinkaii' 'pyrococcus shinkaii']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DWQ OCA].
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==About this Structure==
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==Reference==
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[[4dwq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DWQ OCA].
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<ref group="xtra">PMID:022949672</ref><references group="xtra"/><references/>
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[[Category: Pyrococcus horikoshii]]
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[[Category: Pyrococcus shinkaii]]
[[Category: Englert, M.]]
[[Category: Englert, M.]]
[[Category: Okada, C.]]
[[Category: Okada, C.]]

Revision as of 07:15, 15 January 2014

Template:STRUCTURE 4dwq

Contents

RNA ligase RtcB-GMP/Mn(2+) complex

Template:ABSTRACT PUBMED 22949672

Function

[RTCB_PYRHO] tRNA-splicing ligase that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as a RNA ligase with broad substrate specificity, and may function toward other RNAs (By similarity).

About this Structure

4dwq is a 2 chain structure with sequence from 'pyrococcus shinkaii'. Full crystallographic information is available from OCA.

Reference

  • Englert M, Xia S, Okada C, Nakamura A, Tanavde V, Yao M, Eom SH, Konigsberg WH, Soll D, Wang J. Structural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OH. Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15235-40. Epub 2012 Sep 4. PMID:22949672 doi:http://dx.doi.org/10.1073/pnas.1213795109

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