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3zgg
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_3zgg| PDB=3zgg | SCENE= }} | |
| + | ===Crystal structure of the Fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with NPE caged UDP-Gal (C222(1) space group)=== | ||
| + | {{ABSTRACT_PUBMED_18275942}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN]] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. | ||
| - | + | ==About this Structure== | |
| + | [[3zgg]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZGG OCA]. | ||
| - | + | ==Reference== | |
| + | <ref group="xtra">PMID:018275942</ref><references group="xtra"/><references/> | ||
| + | [[Category: Batot, G O.]] | ||
| + | [[Category: Breton, C.]] | ||
| + | [[Category: Hindsgaul, O.]] | ||
| + | [[Category: Imberty, A.]] | ||
| + | [[Category: Jorgensen, R.]] | ||
| + | [[Category: Palcic, M M.]] | ||
| + | [[Category: Perez, S.]] | ||
| + | [[Category: Royant, A.]] | ||
| + | [[Category: Tanaka, H.]] | ||
| + | [[Category: Catalytic domain]] | ||
| + | [[Category: Glycosyltransferase]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 08:10, 15 January 2014
Contents |
Crystal structure of the Fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with NPE caged UDP-Gal (C222(1) space group)
Template:ABSTRACT PUBMED 18275942
Function
[BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
About this Structure
3zgg is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- Mannerstedt K, Hindsgaul O. Synthesis and photolytic activation of 6-O-2-nitrobenzyl uridine-5'-diphosphogalactose: a 'caged' UDP-Gal derivative. Carbohydr Res. 2008 Apr 7;343(5):875-81. doi: 10.1016/j.carres.2008.01.021. Epub , 2008 Jan 26. PMID:18275942 doi:http://dx.doi.org/10.1016/j.carres.2008.01.021
