4iyr
From Proteopedia
(Difference between revisions)
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- | + | {{STRUCTURE_4iyr| PDB=4iyr | SCENE= }} | |
+ | ===Crystal structure of full-length caspase-6 zymogen=== | ||
- | + | ==Function== | |
+ | [[http://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. | ||
- | + | ==About this Structure== | |
- | + | [[4iyr]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IYR OCA]. | |
- | + | [[Category: Caspase-6]] | |
+ | [[Category: Cao, Q.]] | ||
+ | [[Category: Li, L F.]] | ||
+ | [[Category: Su, X D.]] | ||
+ | [[Category: Wang, X J.]] | ||
+ | [[Category: Caspase fold]] | ||
+ | [[Category: Hydrolase]] | ||
+ | [[Category: Protease]] |
Revision as of 08:22, 15 January 2014
Crystal structure of full-length caspase-6 zymogen
Function
[CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
About this Structure
4iyr is a 2 chain structure. Full crystallographic information is available from OCA.
Categories: Caspase-6 | Cao, Q. | Li, L F. | Su, X D. | Wang, X J. | Caspase fold | Hydrolase | Protease