3a8h
From Proteopedia
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{{STRUCTURE_3a8h| PDB=3a8h | SCENE= }} | {{STRUCTURE_3a8h| PDB=3a8h | SCENE= }} | ||
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===Crystal structure of Nitrile Hydratase mutant S113A complexed with Trimethylacetamide=== | ===Crystal structure of Nitrile Hydratase mutant S113A complexed with Trimethylacetamide=== | ||
| + | {{ABSTRACT_PUBMED_20221653}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/NHAA_RHOER NHAA_RHOER]] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. Industrial production of acrylamide is now being developed using some of the enzymes of this class. [[http://www.uniprot.org/uniprot/NHAB_RHOER NHAB_RHOER]] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3a8h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3a8h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A8H OCA]. |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:020221653</ref><references group="xtra"/> | + | <ref group="xtra">PMID:020221653</ref><references group="xtra"/><references/> |
| + | [[Category: Mycobacterium erythropolis gray and thornton 1928]] | ||
[[Category: Nitrile hydratase]] | [[Category: Nitrile hydratase]] | ||
| - | [[Category: Rhodococcus erythropolis]] | ||
[[Category: Hashimoto, K.]] | [[Category: Hashimoto, K.]] | ||
[[Category: Noguchi, K.]] | [[Category: Noguchi, K.]] | ||
Revision as of 05:54, 22 January 2014
Contents |
Crystal structure of Nitrile Hydratase mutant S113A complexed with Trimethylacetamide
Template:ABSTRACT PUBMED 20221653
Function
[NHAA_RHOER] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. Industrial production of acrylamide is now being developed using some of the enzymes of this class. [NHAB_RHOER] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides.
About this Structure
3a8h is a 2 chain structure with sequence from "mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928. Full crystallographic information is available from OCA.
Reference
- Yamanaka Y, Hashimoto K, Ohtaki A, Noguchi K, Yohda M, Odaka M. Kinetic and structural studies on roles of the serine ligand and a strictly conserved tyrosine residue in nitrile hydratase. J Biol Inorg Chem. 2010 Mar 10. PMID:20221653 doi:10.1007/s00775-010-0632-3
