1xw9

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[[Image:1xw9.png|left|200px]]
 
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{{STRUCTURE_1xw9| PDB=1xw9 | SCENE= }}
{{STRUCTURE_1xw9| PDB=1xw9 | SCENE= }}
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===Drosophila thioredoxin, oxidized, P21===
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{{ABSTRACT_PUBMED_15644209}}
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===Drospohila thioredoxin, oxidized, P21===
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==Function==
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[[http://www.uniprot.org/uniprot/THIO2_DROME THIO2_DROME]] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1.<ref>PMID:11877442</ref>
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{{ABSTRACT_PUBMED_15644209}}
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==About this Structure==
==About this Structure==
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[[1xw9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XW9 OCA].
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[[1xw9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XW9 OCA].
==See Also==
==See Also==
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==Reference==
==Reference==
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<ref group="xtra">PMID:015644209</ref><references group="xtra"/>
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<ref group="xtra">PMID:015644209</ref><references group="xtra"/><references/>
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[[Category: Drosophila melanogaster]]
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[[Category: Drome]]
[[Category: Becker, K.]]
[[Category: Becker, K.]]
[[Category: Hecker, B.]]
[[Category: Hecker, B.]]

Revision as of 06:23, 22 January 2014

Template:STRUCTURE 1xw9

Contents

Drosophila thioredoxin, oxidized, P21

Template:ABSTRACT PUBMED 15644209

Function

[THIO2_DROME] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1.[1]

About this Structure

1xw9 is a 4 chain structure with sequence from Drome. Full crystallographic information is available from OCA.

See Also

Reference

  • Wahl MC, Irmler A, Hecker B, Schirmer RH, Becker K. Comparative structural analysis of oxidized and reduced thioredoxin from Drosophila melanogaster. J Mol Biol. 2005 Feb 4;345(5):1119-30. Epub 2004 Dec 16. PMID:15644209 doi:10.1016/j.jmb.2004.11.004
  1. ↑ Bauer H, Kanzok SM, Schirmer RH. Thioredoxin-2 but not thioredoxin-1 is a substrate of thioredoxin peroxidase-1 from Drosophila melanogaster: isolation and characterization of a second thioredoxin in D. Melanogaster and evidence for distinct biological functions of Trx-1 and Trx-2. J Biol Chem. 2002 May 17;277(20):17457-63. Epub 2002 Mar 4. PMID:11877442 doi:http://dx.doi.org/10.1074/jbc.M200636200

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