3m7o
From Proteopedia
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{{STRUCTURE_3m7o| PDB=3m7o | SCENE= }} | {{STRUCTURE_3m7o| PDB=3m7o | SCENE= }} | ||
===Crystal structure of mouse MD-1 in complex with phosphatidylcholine=== | ===Crystal structure of mouse MD-1 in complex with phosphatidylcholine=== | ||
- | {{ | + | {{ABSTRACT_PUBMED_20595044}} |
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
- | [[3m7o]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3m7o]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M7O OCA]. |
==Reference== | ==Reference== | ||
- | <references group="xtra"/><references/> | + | <ref group="xtra">PMID:020595044</ref><references group="xtra"/><references/> |
- | [[Category: | + | [[Category: Lk3 transgenic mice]] |
[[Category: Harada, H.]] | [[Category: Harada, H.]] | ||
[[Category: Ohto, U.]] | [[Category: Ohto, U.]] |
Revision as of 06:31, 22 January 2014
Contents |
Crystal structure of mouse MD-1 in complex with phosphatidylcholine
Template:ABSTRACT PUBMED 20595044
Function
[LY86_MOUSE] May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression.[1]
About this Structure
3m7o is a 4 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.
Reference
- Harada H, Ohto U, Satow Y. Crystal structure of mouse MD-1 with endogenous phospholipid bound in its cavity. J Mol Biol. 2010 Jul 23;400(4):838-46. Epub 2010 Jun 1. PMID:20595044 doi:http://dx.doi.org/10.1016/j.jmb.2010.05.063