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| - | {{STRUCTURE_3vdo| PDB=3vdo | SCENE= }}
| + | #REDIRECT [[4nqw]] This PDB entry is obsolete and replaced by 4nqw |
| - | ===Structure of extra-cytoplasmic function(ECF) sigma factor SigK in complex with its negative regulator RskA from Mycobacterium tuberculosis===
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| - | ==Function==
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| - | [[http://www.uniprot.org/uniprot/SIGK_MYCTU SIGK_MYCTU]] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-K controls genes such as mpt70 and mpt83. [[http://www.uniprot.org/uniprot/RSKA_MYCTU RSKA_MYCTU]] Represses SigK, the extracytoplasmic function (ECF) sigma factor K, by binding to it and inhibiting its activity. This leads to a decreased expression of SigK-regulated genes, such as mpt70 and mpt83. | + | |
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| - | ==About this Structure==
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| - | [[3vdo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VDO OCA].
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| - | [[Category: Mycobacterium tuberculosis]]
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| - | [[Category: Gopal, B.]]
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| - | [[Category: Shukla, J K.]]
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| - | [[Category: Dna]]
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| - | [[Category: Dna binding protein-protein binding complex]]
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| - | [[Category: Ecf sigma factor]]
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| - | [[Category: Promoter dna binding]]
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| - | [[Category: Recognition and transcription initiation]]
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Current revision
- REDIRECT 4nqw This PDB entry is obsolete and replaced by 4nqw
