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3w45

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_3w45| PDB=3w45 | SCENE= }}
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===Crystal structure of RsbX in complex with cobalt in space group P1===
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The entry 3w45 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/RSBX_BACSU RSBX_BACSU]] Negative regulator of sigma-B activity. Dephosphorylates RsbS. Plays a role both in maintaining low sigma-B activity during growth and in reestablishing prestress sigma-B activity after induction. Could have a negative feedback role by indirectly communicating sigma-B protein levels.<ref>PMID:1592822</ref> <ref>PMID:8468294</ref> <ref>PMID:8824586</ref> <ref>PMID:9658013</ref>
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Authors: Makino, M., Teh, A.H., Baba, S., Shimizu, N., Yamamoto, M., Kumasaka, T.
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==About this Structure==
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[[3w45]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W45 OCA].
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Description: Crystal structure of RsbX in complex with cobalt in space group P1
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Phosphoserine phosphatase]]
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[[Category: Baba, S.]]
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[[Category: Kumasaka, T.]]
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[[Category: Makino, M.]]
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[[Category: Shimizu, N.]]
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[[Category: Teh, A H.]]
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[[Category: Yamamoto, M.]]
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[[Category: Alpha-beta beta-alpha sandwich fold]]
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[[Category: Dephosphorylation]]
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[[Category: Environmental stress]]
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[[Category: Gene expression regulation]]
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[[Category: Hydrolase]]
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[[Category: Magnesium/manganese binding]]
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[[Category: Phosphatase]]
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[[Category: Phosphoric monoester hydrolase]]
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[[Category: Protein phosphatase]]
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[[Category: Signaling protein]]
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[[Category: Stressosome]]
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[[Category: Tertiary]]

Revision as of 07:00, 22 January 2014

Template:STRUCTURE 3w45

Contents

Crystal structure of RsbX in complex with cobalt in space group P1

Function

[RSBX_BACSU] Negative regulator of sigma-B activity. Dephosphorylates RsbS. Plays a role both in maintaining low sigma-B activity during growth and in reestablishing prestress sigma-B activity after induction. Could have a negative feedback role by indirectly communicating sigma-B protein levels.[1] [2] [3] [4]

About this Structure

3w45 is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Boylan SA, Rutherford A, Thomas SM, Price CW. Activation of Bacillus subtilis transcription factor sigma B by a regulatory pathway responsive to stationary-phase signals. J Bacteriol. 1992 Jun;174(11):3695-706. PMID:1592822
  2. ↑ Benson AK, Haldenwang WG. Regulation of sigma B levels and activity in Bacillus subtilis. J Bacteriol. 1993 Apr;175(8):2347-56. PMID:8468294
  3. ↑ Yang X, Kang CM, Brody MS, Price CW. Opposing pairs of serine protein kinases and phosphatases transmit signals of environmental stress to activate a bacterial transcription factor. Genes Dev. 1996 Sep 15;10(18):2265-75. PMID:8824586
  4. ↑ Smirnova N, Scott J, Voelker U, Haldenwang WG. Isolation and characterization of Bacillus subtilis sigB operon mutations that suppress the loss of the negative regulator RsbX. J Bacteriol. 1998 Jul;180(14):3671-80. PMID:9658013

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