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3aq0

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[[Image:3aq0.png|left|200px]]
 
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{{STRUCTURE_3aq0| PDB=3aq0 | SCENE= }}
{{STRUCTURE_3aq0| PDB=3aq0 | SCENE= }}
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===Ligand-bound form of Arabidopsis medium/long-chain length prenyl pyrophosphate synthase (surface polar residue mutant)===
===Ligand-bound form of Arabidopsis medium/long-chain length prenyl pyrophosphate synthase (surface polar residue mutant)===
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{{ABSTRACT_PUBMED_21220764}}
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{{ABSTRACT_PUBMED_21220764}}
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==Function==
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[[http://www.uniprot.org/uniprot/SPS3_ARATH SPS3_ARATH]] May be involved in the supply of solanesyl diphosphate for ubiquinone-9 biosynthesis in mitochondria. Synthesizes C25 to C45 medium / long-chain products depending on the type of substrate available. Can use geranyl diphosphate, farnesyl diphosphate or geranylgeranyl diphosphate as substrates, but not dimethylallyl diphosphate.<ref>PMID:11069698</ref> <ref>PMID:17877699</ref> <ref>PMID:21950843</ref> <ref>PMID:21220764</ref>
==About this Structure==
==About this Structure==
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[[3aq0]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AQ0 OCA].
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[[3aq0]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AQ0 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:021220764</ref><references group="xtra"/>
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<ref group="xtra">PMID:021220764</ref><references group="xtra"/><references/>
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[[Category: Arabidopsis thaliana]]
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[[Category: Arath]]
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[[Category: Trans-hexaprenyltranstransferase]]
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[[Category: Heptaprenyl diphosphate synthase]]
[[Category: Chang, T H.]]
[[Category: Chang, T H.]]
[[Category: Hsieh, F L.]]
[[Category: Hsieh, F L.]]

Revision as of 05:35, 29 January 2014

Template:STRUCTURE 3aq0

Contents

Ligand-bound form of Arabidopsis medium/long-chain length prenyl pyrophosphate synthase (surface polar residue mutant)

Template:ABSTRACT PUBMED 21220764

Function

[SPS3_ARATH] May be involved in the supply of solanesyl diphosphate for ubiquinone-9 biosynthesis in mitochondria. Synthesizes C25 to C45 medium / long-chain products depending on the type of substrate available. Can use geranyl diphosphate, farnesyl diphosphate or geranylgeranyl diphosphate as substrates, but not dimethylallyl diphosphate.[1] [2] [3] [4]

About this Structure

3aq0 is a 8 chain structure with sequence from Arath. Full crystallographic information is available from OCA.

Reference

  • Hsieh FL, Chang TH, Ko TP, Wang AH. Structure and mechanism of an Arabidopsis medium/long-chain length prenyl pyrophosphate synthase. Plant Physiol. 2011 Jan 10. PMID:21220764 doi:10.1104/pp.110.168799
  1. ↑ Bouvier F, Suire C, d'Harlingue A, Backhaus RA, Camara B. Molecular cloning of geranyl diphosphate synthase and compartmentation of monoterpene synthesis in plant cells. Plant J. 2000 Oct;24(2):241-52. PMID:11069698
  2. ↑ van Schie CC, Ament K, Schmidt A, Lange T, Haring MA, Schuurink RC. Geranyl diphosphate synthase is required for biosynthesis of gibberellins. Plant J. 2007 Nov;52(4):752-62. Epub 2007 Sep 18. PMID:17877699 doi:http://dx.doi.org/10.1111/j.1365-313X.2007.03273.x
  3. ↑ Ducluzeau AL, Wamboldt Y, Elowsky CG, Mackenzie SA, Schuurink RC, Basset GJ. Gene network reconstruction identifies the authentic trans-prenyl diphosphate synthase that makes the solanesyl moiety of ubiquinone-9 in Arabidopsis. Plant J. 2012 Jan;69(2):366-75. doi: 10.1111/j.1365-313X.2011.04796.x. Epub 2011 , Oct 25. PMID:21950843 doi:http://dx.doi.org/10.1111/j.1365-313X.2011.04796.x
  4. ↑ Hsieh FL, Chang TH, Ko TP, Wang AH. Structure and mechanism of an Arabidopsis medium/long-chain length prenyl pyrophosphate synthase. Plant Physiol. 2011 Jan 10. PMID:21220764 doi:10.1104/pp.110.168799

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