This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2c7q
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:2c7q.png|left|200px]] | ||
| - | |||
{{STRUCTURE_2c7q| PDB=2c7q | SCENE= }} | {{STRUCTURE_2c7q| PDB=2c7q | SCENE= }} | ||
| + | ===HhaI DNA methyltransferase complex with oligonucleotide containing 2- aminopurine outside the recognition sequence (paired with G) and SAH=== | ||
| + | {{ABSTRACT_PUBMED_16340006}} | ||
| - | == | + | ==Function== |
| - | + | [[http://www.uniprot.org/uniprot/MTH1_HAEPH MTH1_HAEPH]] This methylase recognizes the double-stranded sequence GCGC, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the HhaI endonuclease. | |
| - | + | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2c7q]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[2c7q]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_x"_pritchett_and_stillman_1919 "bacillus x" pritchett and stillman 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C7Q OCA]. |
==See Also== | ==See Also== | ||
*[[DNA methyltransferase|DNA methyltransferase]] | *[[DNA methyltransferase|DNA methyltransferase]] | ||
| + | *[[HhaI DNA methyltransferase|HhaI DNA methyltransferase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:016340006</ref><references group="xtra"/> | + | <ref group="xtra">PMID:016340006</ref><references group="xtra"/><references/> |
| - | [[Category: | + | [[Category: Bacillus x pritchett and stillman 1919]] |
[[Category: Daujotyte, D.]] | [[Category: Daujotyte, D.]] | ||
[[Category: Grazulis, S.]] | [[Category: Grazulis, S.]] | ||
[[Category: Base flipping]] | [[Category: Base flipping]] | ||
| - | [[Category: Dna methyltransferase]] | ||
| - | [[Category: Methyltransferase]] | ||
[[Category: Restriction system]] | [[Category: Restriction system]] | ||
| - | [[Category: Transferase]] | + | [[Category: Transferase-dna complex]] |
Revision as of 06:21, 29 January 2014
Contents |
HhaI DNA methyltransferase complex with oligonucleotide containing 2- aminopurine outside the recognition sequence (paired with G) and SAH
Template:ABSTRACT PUBMED 16340006
Function
[MTH1_HAEPH] This methylase recognizes the double-stranded sequence GCGC, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the HhaI endonuclease.
About this Structure
2c7q is a 3 chain structure with sequence from "bacillus_x"_pritchett_and_stillman_1919 "bacillus x" pritchett and stillman 1919. Full crystallographic information is available from OCA.
See Also
Reference
- Neely RK, Daujotyte D, Grazulis S, Magennis SW, Dryden DT, Klimasauskas S, Jones AC. Time-resolved fluorescence of 2-aminopurine as a probe of base flipping in M.HhaI-DNA complexes. Nucleic Acids Res. 2005 Dec 9;33(22):6953-60. Print 2005. PMID:16340006 doi:http://dx.doi.org/33/22/6953
