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3zj3

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'''Unreleased structure'''
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{{STRUCTURE_3zj3| PDB=3zj3 | SCENE= }}
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===Structure of Clostridium perfringens Enterotoxin with a peptide derived from a modified version of ECL-2 of Claudin 2===
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{{ABSTRACT_PUBMED_21839091}}
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The entry 3zj3 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/CLD2_MOUSE CLD2_MOUSE]] Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.<ref>PMID:10508613</ref> [[http://www.uniprot.org/uniprot/ELTB_CLOPF ELTB_CLOPF]] This enterotoxin is responsible for many cases of a mild type of food poisoning.
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Authors: Yelland, T., Naylor, C.E., Savva, C.G., Basak, A.K.
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==About this Structure==
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[[3zj3]] is a 30 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZJ3 OCA].
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Description: Structure of Clostridium perfringens Enterotoxin with a peptide derived from a modified version of ECL-2 of Claudin 2
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==Reference==
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<ref group="xtra">PMID:021839091</ref><references group="xtra"/><references/>
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[[Category: Basak, A K.]]
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[[Category: Naylor, C E.]]
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[[Category: Savva, C G.]]
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[[Category: Yelland, T.]]
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[[Category: Beta pore-forming toxin]]
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[[Category: Receptor binding]]
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[[Category: Toxin-cell adhesion complex]]

Revision as of 07:37, 29 January 2014

Template:STRUCTURE 3zj3

Contents

Structure of Clostridium perfringens Enterotoxin with a peptide derived from a modified version of ECL-2 of Claudin 2

Template:ABSTRACT PUBMED 21839091

Function

[CLD2_MOUSE] Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.[1] [ELTB_CLOPF] This enterotoxin is responsible for many cases of a mild type of food poisoning.

About this Structure

3zj3 is a 30 chain structure. Full crystallographic information is available from OCA.

Reference

  • Briggs DC, Naylor CE, Smedley JG 3rd, Lukoyanova N, Robertson S, Moss DS, McClane BA, Basak AK. Structure of the Food-Poisoning Clostridium perfringens Enterotoxin Reveals Similarity to the Aerolysin-Like Pore-Forming Toxins. J Mol Biol. 2011 Oct 14;413(1):138-49. Epub 2011 Aug 3. PMID:21839091 doi:10.1016/j.jmb.2011.07.066
  1. ↑ Kubota K, Furuse M, Sasaki H, Sonoda N, Fujita K, Nagafuchi A, Tsukita S. Ca(2+)-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions. Curr Biol. 1999 Sep 23;9(18):1035-8. PMID:10508613

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