4l2o
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4l2o| PDB=4l2o | SCENE= }} | |
| + | ===Crystal structure of human ALDH3A1 with its selective inhibitor 1-(4-fluorophenyl)sulfonyl-2-methylbenzimidazole=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/AL3A1_HUMAN AL3A1_HUMAN]] ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes. | ||
| - | + | ==About this Structure== | |
| - | + | [[4l2o]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L2O OCA]. | |
| - | + | [[Category: Hurley, T D.]] | |
| + | [[Category: Parajuli, B.]] | ||
| + | [[Category: Catalyzes benzaldehyde]] | ||
| + | [[Category: Dehydrogenase]] | ||
| + | [[Category: Nadp+ binding]] | ||
| + | [[Category: Oxidoreductase-inhibitor complex]] | ||
| + | [[Category: Rossman fold]] | ||
Revision as of 07:48, 29 January 2014
Crystal structure of human ALDH3A1 with its selective inhibitor 1-(4-fluorophenyl)sulfonyl-2-methylbenzimidazole
Function
[AL3A1_HUMAN] ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.
About this Structure
4l2o is a 4 chain structure. Full crystallographic information is available from OCA.
