4mi8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_4mi8| PDB=4mi8 | SCENE= }}
 +
===Crystal structure of the complex of murine gamma-herpesvirus 68 Bcl-2 homolog M11 and a Beclin 1 BH3 domain-derived peptide===
-
The entry 4mi8 is ON HOLD until Paper Publication
+
==Function==
 +
[[http://www.uniprot.org/uniprot/BECN1_HUMAN BECN1_HUMAN]] Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.<ref>PMID:20208530</ref>
-
Authors: Su, M., Mei, Y.
+
==About this Structure==
 +
[[4mi8]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MI8 OCA].
-
Description: Crystal structure of the complex of murine gamma-herpesvirus 68 Bcl-2 homolog M11 and a Beclin 1 BH3 domain-derived peptide
+
==Reference==
 +
<references group="xtra"/><references/>
 +
[[Category: Mei, Y.]]
 +
[[Category: Su, M.]]
 +
[[Category: Anti-apoptotic and anti-autophagic activity]]
 +
[[Category: Bcl-2 family]]
 +
[[Category: Bh3d]]
 +
[[Category: Viral protein-apoptosis complex]]

Revision as of 07:50, 29 January 2014

Template:STRUCTURE 4mi8

Contents

Crystal structure of the complex of murine gamma-herpesvirus 68 Bcl-2 homolog M11 and a Beclin 1 BH3 domain-derived peptide

Function

[BECN1_HUMAN] Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.[1]

About this Structure

4mi8 is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Sagona AP, Nezis IP, Pedersen NM, Liestol K, Poulton J, Rusten TE, Skotheim RI, Raiborg C, Stenmark H. PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody. Nat Cell Biol. 2010 Apr;12(4):362-71. doi: 10.1038/ncb2036. Epub 2010 Mar 7. PMID:20208530 doi:http://dx.doi.org/10.1038/ncb2036

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4mi8"
Personal tools