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4ad6
From Proteopedia
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{{STRUCTURE_4ad6| PDB=4ad6 | SCENE= }} | {{STRUCTURE_4ad6| PDB=4ad6 | SCENE= }} | ||
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===Synthesis and SAR of guanine based analogues for HPPK inhibitors=== | ===Synthesis and SAR of guanine based analogues for HPPK inhibitors=== | ||
| - | + | {{ABSTRACT_PUBMED_23565155}} | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
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[[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]] | [[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]] | ||
[[Category: Chhabra, S.]] | [[Category: Chhabra, S.]] | ||
Revision as of 08:16, 5 February 2014
Synthesis and SAR of guanine based analogues for HPPK inhibitors
Template:ABSTRACT PUBMED 23565155
About this Structure
4ad6 is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- Chhabra S, Barlow N, Dolezal O, Hattarki MK, Newman J, Peat TS, Graham B, Swarbrick JD. Exploring the chemical space around 8-mercaptoguanine as a route to new inhibitors of the folate biosynthesis enzyme HPPK. PLoS One. 2013;8(4):e59535. doi: 10.1371/journal.pone.0059535. Epub 2013 Apr 2. PMID:23565155 doi:http://dx.doi.org/10.1371/journal.pone.0059535
