2r0k

(Difference between revisions)

Revision as of 08:17, 5 February 2014

[HGFA_HUMAN] Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.

2r0k is a 3 chain structure with sequence from [1] and Human. Full crystallographic information is available from OCA.

Wu Y, Eigenbrot C, Liang WC, Stawicki S, Shia S, Fan B, Ganesan R, Lipari MT, Kirchhofer D. Structural insight into distinct mechanisms of protease inhibition by antibodies. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19784-9. Epub 2007 Dec 5. PMID:18077410

@@ Line 1: / Line 1: @@
-[[Image:2r0k.png|left|200px]]
 {{STRUCTURE_2r0k|  PDB=2r0k  |  SCENE=  }}
 ===Protease domain of HGFA with inhibitor Fab58===
+{{ABSTRACT_PUBMED_18077410}}
-{{ABSTRACT_PUBMED_18077410}}
+==Function==
+[[http://www.uniprot.org/uniprot/HGFA_HUMAN HGFA_HUMAN]] Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.
 ==About this Structure==
-[[2r0k]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R0K OCA].
+[[2r0k]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R0K OCA].
 ==See Also==
@@ Line 14: / Line 13: @@
 ==Reference==
-<ref group="xtra">PMID:018077410</ref><references group="xtra"/>
+<ref group="xtra">PMID:018077410</ref><references group="xtra"/><references/>
-[[Category: Homo sapiens]]
+[[Category: Human]]
 [[Category: Eigenbrot, C.]]
 [[Category: Shia, S.]]