4jy5
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_4jy5| PDB=4jy5 | SCENE= }} | {{STRUCTURE_4jy5| PDB=4jy5 | SCENE= }} | ||
===Crystal structure of human Fab PGT122, a broadly reactive and potent HIV-1 neutralizing antibody=== | ===Crystal structure of human Fab PGT122, a broadly reactive and potent HIV-1 neutralizing antibody=== | ||
+ | {{ABSTRACT_PUBMED_23658524}} | ||
==About this Structure== | ==About this Structure== | ||
- | [[4jy5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[4jy5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JY5 OCA]. |
- | [[Category: | + | |
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:023658524</ref><references group="xtra"/><references/> | ||
+ | [[Category: Human]] | ||
[[Category: Burton, D R.]] | [[Category: Burton, D R.]] | ||
[[Category: Diwanji, D C.]] | [[Category: Diwanji, D C.]] |
Revision as of 08:44, 5 February 2014
Crystal structure of human Fab PGT122, a broadly reactive and potent HIV-1 neutralizing antibody
Template:ABSTRACT PUBMED 23658524
About this Structure
4jy5 is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA.
Reference
- Julien JP, Sok D, Khayat R, Lee JH, Doores KJ, Walker LM, Ramos A, Diwanji DC, Pejchal R, Cupo A, Katpally U, Depetris RS, Stanfield RL, McBride R, Marozsan AJ, Paulson JC, Sanders RW, Moore JP, Burton DR, Poignard P, Ward AB, Wilson IA. Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans. PLoS Pathog. 2013 May;9(5):e1003342. doi: 10.1371/journal.ppat.1003342. Epub 2013, May 2. PMID:23658524 doi:10.1371/journal.ppat.1003342