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4lzb

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{{STRUCTURE_4lzb| PDB=4lzb | SCENE= }}
{{STRUCTURE_4lzb| PDB=4lzb | SCENE= }}
===Uracil binding pocket in Vaccinia virus uracil DNA glycosylase===
===Uracil binding pocket in Vaccinia virus uracil DNA glycosylase===
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{{ABSTRACT_PUBMED_24316823}}
==Function==
==Function==
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==About this Structure==
==About this Structure==
[[4lzb]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LZB OCA].
[[4lzb]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LZB OCA].
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==Reference==
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<ref group="xtra">PMID:024316823</ref><references group="xtra"/><references/>
[[Category: Uracil-DNA glycosylase]]
[[Category: Uracil-DNA glycosylase]]
[[Category: Chattopadhyay, D.]]
[[Category: Chattopadhyay, D.]]

Revision as of 09:11, 5 February 2014

Template:STRUCTURE 4lzb

Contents

Uracil binding pocket in Vaccinia virus uracil DNA glycosylase

Template:ABSTRACT PUBMED 24316823

Function

[UNG_VACCA] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA.

About this Structure

4lzb is a 12 chain structure. Full crystallographic information is available from OCA.

Reference

  • Schormann N, Banerjee S, Ricciardi R, Chattopadhyay D. Structure of the uracil complex of Vaccinia virus uracil DNA glycosylase. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Dec;69(Pt 12):1328-34., doi: 10.1107/S1744309113030613. Epub 2013 Nov 28. PMID:24316823 doi:http://dx.doi.org/10.1107/S1744309113030613

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