2biv
From Proteopedia
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- | [[Image:2biv.png|left|200px]] | ||
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{{STRUCTURE_2biv| PDB=2biv | SCENE= }} | {{STRUCTURE_2biv| PDB=2biv | SCENE= }} | ||
+ | ===Crystal structure of the wild-type MBT domains of Human SCML2=== | ||
+ | {{ABSTRACT_PUBMED_18706910}} | ||
- | == | + | ==Function== |
+ | [[http://www.uniprot.org/uniprot/SCML2_HUMAN SCML2_HUMAN]] Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity). | ||
+ | ==About this Structure== | ||
+ | [[2biv]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIV OCA]. | ||
- | == | + | ==Reference== |
- | + | <ref group="xtra">PMID:018706910</ref><references group="xtra"/><references/> | |
- | [[Category: | + | [[Category: Human]] |
[[Category: Allen, M D.]] | [[Category: Allen, M D.]] | ||
[[Category: Bycroft, M.]] | [[Category: Bycroft, M.]] | ||
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[[Category: Santiveri, C M.]] | [[Category: Santiveri, C M.]] | ||
[[Category: Malignant brain tumor]] | [[Category: Malignant brain tumor]] | ||
- | [[Category: | + | [[Category: Transcription]] |
- | + | ||
[[Category: Transcription factor]] | [[Category: Transcription factor]] |
Revision as of 09:21, 5 February 2014
Contents |
Crystal structure of the wild-type MBT domains of Human SCML2
Template:ABSTRACT PUBMED 18706910
Function
[SCML2_HUMAN] Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity).
About this Structure
2biv is a 3 chain structure with sequence from Human. Full crystallographic information is available from OCA.
Reference
- Santiveri CM, Lechtenberg BC, Allen MD, Sathyamurthy A, Jaulent AM, Freund SM, Bycroft M. The malignant brain tumor repeats of human SCML2 bind to peptides containing monomethylated lysine. J Mol Biol. 2008 Oct 24;382(5):1107-12. Epub 2008 Aug 3. PMID:18706910 doi:10.1016/j.jmb.2008.07.081