1agg

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[[Image:1agg.png|left|200px]]
 
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{{STRUCTURE_1agg| PDB=1agg | SCENE= }}
{{STRUCTURE_1agg| PDB=1agg | SCENE= }}
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===THE SOLUTION STRUCTURE OF OMEGA-AGA-IVB, A P-TYPE CALCIUM CHANNEL ANTAGONIST FROM THE VENOM OF AGELENOPSIS APERTA===
===THE SOLUTION STRUCTURE OF OMEGA-AGA-IVB, A P-TYPE CALCIUM CHANNEL ANTAGONIST FROM THE VENOM OF AGELENOPSIS APERTA===
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{{ABSTRACT_PUBMED_7703698}}
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{{ABSTRACT_PUBMED_7703698}}
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==Function==
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[[http://www.uniprot.org/uniprot/TOG4B_AGEAP TOG4B_AGEAP]] Antagonist of voltage-gated Cav2.1/CACNA1A (P-type) calcium channels. Paralyzes insect by blocking neuromuscular transmission.<ref>PMID:8232218</ref>
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:007703698</ref><references group="xtra"/>
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<ref group="xtra">PMID:007703698</ref><references group="xtra"/><references/>
[[Category: Agelenopsis aperta]]
[[Category: Agelenopsis aperta]]
[[Category: Adams, M E.]]
[[Category: Adams, M E.]]

Revision as of 09:32, 5 February 2014

Template:STRUCTURE 1agg

Contents

THE SOLUTION STRUCTURE OF OMEGA-AGA-IVB, A P-TYPE CALCIUM CHANNEL ANTAGONIST FROM THE VENOM OF AGELENOPSIS APERTA

Template:ABSTRACT PUBMED 7703698

Function

[TOG4B_AGEAP] Antagonist of voltage-gated Cav2.1/CACNA1A (P-type) calcium channels. Paralyzes insect by blocking neuromuscular transmission.[1]

About this Structure

1agg is a 1 chain structure with sequence from Agelenopsis aperta. Full experimental information is available from OCA.

Reference

  • Reily MD, Thanabal V, Adams ME. The solution structure of omega-Aga-IVB, a P-type calcium channel antagonist from venom of the funnel web spider, Agelenopsis aperta. J Biomol NMR. 1995 Feb;5(2):122-32. PMID:7703698
  1. Adams ME, Mintz IM, Reily MD, Thanabal V, Bean BP. Structure and properties of omega-agatoxin IVB, a new antagonist of P-type calcium channels. Mol Pharmacol. 1993 Oct;44(4):681-8. PMID:8232218

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